Nail as a Window to Diagnosing Multisystem Langerhans Cell Histiocytosis: A Case Report and Review of Literature.

IF 1.1 4区医学 Q4 DERMATOLOGY

American Journal of Dermatopathology Pub Date : 2024-11-01 Epub Date: 2024-08-14 DOI:10.1097/DAD.0000000000002818

Arun Somasundaram, Senthil Kumar Periyasamy, Narayanan Arunachalam, Tirekha Suyamprakasam Vimala, Sree Rekha Jinkala, Gunasekaran Dhandapany, Ramassamy Sivaranjini

引用次数: 0

Abstract

Abstract: Nail involvement in Langerhans cell histiocytosis is rarely reported in the literature. According to the reported cases, it is believed that the involvement of nails has a poor prognosis because of multisystem involvement. Performing a nail bed biopsy might be challenging for children. We report a child in whom nail bed biopsy served as the sole clue to the diagnosis of Langerhans cell histiocytosis in absentia of skin clue on a background of advanced multisystem involvement.

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指甲是诊断多系统朗格汉斯细胞组织细胞增生症的窗口：病例报告与文献综述。

摘要：朗格汉斯细胞组织细胞增生症累及指甲的文献报道很少。根据已报道的病例，由于多系统受累，指甲受累的预后较差。对儿童来说，进行甲床活检可能具有挑战性。我们报告了一名患儿，在晚期多系统受累的背景下，甲床活检是诊断朗格汉斯细胞组织细胞增生症的唯一线索，而皮肤线索缺失。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American Journal of Dermatopathology 医学-皮肤病学

CiteScore

1.80

自引率

9.10%

发文量

453

审稿时长

3 months

期刊介绍： The American Journal of Dermatopathology offers outstanding coverage of the latest diagnostic approaches and laboratory techniques, as well as insights into contemporary social, legal, and ethical concerns. Each issue features review articles on clinical, technical, and basic science advances and illuminating, detailed case reports. With the The American Journal of Dermatopathology you''ll be able to: -Incorporate step-by-step coverage of new or difficult-to-diagnose conditions from their earliest histopathologic signs to confirmatory immunohistochemical and molecular studies. -Apply the latest basic science findings and clinical approaches to your work right away. -Tap into the skills and expertise of your peers and colleagues the world over peer-reviewed original articles, "Extraordinary cases reports", coverage of practical guidelines, and graphic presentations. -Expand your horizons through the Journal''s idea-generating forum for debating controversial issues and learning from preeminent researchers and clinicians