CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target.

IF 13.3 1区医学 Q1 MEDICINE, RESEARCH & EXPERIMENTAL

Journal of Clinical Investigation Pub Date : 2024-08-15 DOI:10.1172/JCI184305

Quy Le, Brandon Hadland, Jenny L Smith, Amanda Leonti, Benjamin J Huang, Rhonda Ries, Tiffany A Hylkema, Sommer Castro, Thao T Tang, Cyd N McKay, LaKeisha Perkins, Laura Pardo, Jay Sarthy, Amy K Beckman, Robin Williams, Rhonda Idemmili, Scott Furlan, Takashi Ishida, Lindsey Call, Shivani Srivastava, Anisha M Loeb, Filippo Milano, Suzan Imren, Shelli M Morris, Fiona Pakiam, Jim M Olson, Michael R Loken, Lisa Brodersen, Stanley R Riddell, Katherine Tarlock, Irwin D Bernstein, Keith R Loeb, Soheil Meshinchi

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CBFA2T3-GLIS2小儿急性巨核细胞白血病模型确定FOLR1为CAR T细胞靶点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Clinical Investigation 医学-医学：研究与实验

CiteScore

24.50

自引率

1.30%

发文量

1034

审稿时长

2 months

期刊介绍： The Journal of Clinical Investigation, established in 1924 by the ASCI, is a prestigious publication that focuses on breakthroughs in basic and clinical biomedical science, with the goal of advancing the field of medicine. With an impressive Impact Factor of 15.9 in 2022, it is recognized as one of the leading journals in the "Medicine, Research & Experimental" category of the Web of Science. The journal attracts a diverse readership from various medical disciplines and sectors. It publishes a wide range of research articles encompassing all biomedical specialties, including Autoimmunity, Gastroenterology, Immunology, Metabolism, Nephrology, Neuroscience, Oncology, Pulmonology, Vascular Biology, and many others. The Editorial Board consists of esteemed academic editors who possess extensive expertise in their respective fields. They are actively involved in research, ensuring the journal's high standards of publication and scientific rigor.