Evidence of Structural Proteins of Toxoplasma gondii in Sera of Experimentally Infected Mice

Abstract

The present study was performed to clarify whether structural proteins are constituants of the antigens of Toxoplasma gondii which circulate in the sera of experimentally infected mice. Rabbits were immunized with mice sera containing circulating antigen, the rabbit sera were then tested for antibodies against Toxoplasma gondii. Low titers of specific antibodies, directed against cell wall proteins, could be detected. Thus, the circulating antigen must at least partially consist of structural proteins.