Simulated-use evaluation of rapid ChannelCheck™ cleaning test for optimal detection of organic residues in flexible endoscope channels

IF 3.9 3区医学 Q1 INFECTIOUS DISEASES

Journal of Hospital Infection Pub Date : 2024-08-10 DOI:10.1016/j.jhin.2024.07.013

K. Kulkarni , M. Gavette , M.J. Alfa

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引用次数: 0

Abstract

Background

The need to monitor manual cleaning of high-risk endoscopes is recommended or more so required by the current endoscope reprocessing guidelines. The objective of this study was to establish the optimal extraction volume for colonoscopes and bronchoscopes and demonstrate the extraction efficacy for the ChannelCheck™ rapid test.

Methods

The test soil utilized as a positive control was ATS2015 containing 20% defibrinated bovine blood. The extraction from the instrument channel of a colonoscope and bronchoscope was evaluated to establish the optimal extraction volume and the extraction efficacy for protein, carbohydrate and haemoglobin.

Results

Of the extraction volumes tested, 10 mL was optimal for both colonoscopes and bronchoscopes. The extraction efficacy was 91% for carbohydrate, 83.7% for haemoglobin and 82.4% for protein.

Conclusions

The limit of detection for these analytes by the ChannelCheck rapid test meet or exceed the established levels that correlate with adequate manual cleaning of flexible endoscopes.

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对快速 ChannelCheck™ 清洁测试进行模拟使用评估，以优化柔性内窥镜通道中有机残留物的检测。

背景：目前的内窥镜再处理指南建议或要求对高风险内窥镜的人工清洗进行监测。本研究的目的是确定结肠镜和支气管镜的最佳提取量，并证明 ChannelCheck™ 快速检测的提取效果：用作阳性对照的测试土壤是含有 20% 去纤维牛血的 ATS2015。评估了从结肠镜和支气管镜的器械通道中的提取情况，以确定最佳提取量以及蛋白质、碳水化合物和血红蛋白的提取效果：结果：在测试的提取量中，10 毫升是结肠镜和支气管镜的最佳提取量。碳水化合物的提取率为 91%，血红蛋白的提取率为 83.7%，蛋白质的提取率为 82.4%：结论：ChannelCheck 快速检测仪对这些分析物的检测限达到或超过了既定水平，这与对柔性内窥镜进行充分的人工清洁有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Hospital Infection 医学-传染病学

CiteScore

12.70

自引率

5.80%

发文量

271

审稿时长

19 days

期刊介绍： The Journal of Hospital Infection is the editorially independent scientific publication of the Healthcare Infection Society. The aim of the Journal is to publish high quality research and information relating to infection prevention and control that is relevant to an international audience. The Journal welcomes submissions that relate to all aspects of infection prevention and control in healthcare settings. This includes submissions that: provide new insight into the epidemiology, surveillance, or prevention and control of healthcare-associated infections and antimicrobial resistance in healthcare settings; provide new insight into cleaning, disinfection and decontamination; provide new insight into the design of healthcare premises; describe novel aspects of outbreaks of infection; throw light on techniques for effective antimicrobial stewardship; describe novel techniques (laboratory-based or point of care) for the detection of infection or antimicrobial resistance in the healthcare setting, particularly if these can be used to facilitate infection prevention and control; improve understanding of the motivations of safe healthcare behaviour, or describe techniques for achieving behavioural and cultural change; improve understanding of the use of IT systems in infection surveillance and prevention and control.