Extrapyramidal Syndrome due to Aripiprazole Overdose in a Young Woman: An Unusual Case Report.

IF 0.8 Q3 MEDICINE, GENERAL & INTERNAL
Case Reports in Medicine Pub Date : 2024-08-05 eCollection Date: 2024-01-01 DOI:10.1155/2024/8883047
Homa Talabaki, Ensiyeh Taghizadeh, Zakaria Zakariaei
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引用次数: 0

Abstract

Aripiprazole is an atypical antipsychotic medication indicated for the treatment of schizophrenia and bipolar disorders. The drug has been shown to exhibit acceptable efficacy and is often preferred as a first-line psychiatric treatment option owing to its lower incidence of adverse effects. While first-generation antipsychotics are associated with extrapyramidal syndrome (EPS), atypical antipsychotics such as aripiprazole are generally associated with a lower frequency of EPS. In this case, we present a 31-year-old woman with a history of bipolar disorder who developed EPS after ingesting 200 mg of aripiprazole. Fortunately, her symptoms improved with the administration of biperiden, and she was discharged five days after ingestion. This case highlights the potential for significant consequences associated with aripiprazole, even within its therapeutic index.

一名年轻女性因阿立哌唑过量导致锥体外系综合征:一个不寻常的病例报告
阿立哌唑是一种非典型抗精神病药物,适用于治疗精神分裂症和躁狂症。该药已被证明具有可接受的疗效,由于其不良反应发生率较低,通常被首选作为一线精神病治疗药物。虽然第一代抗精神病药物与锥体外系综合征(EPS)有关,但阿立哌唑等非典型抗精神病药物发生 EPS 的频率通常较低。在本病例中,我们介绍了一名有躁郁症病史的 31 岁女性,她在服用 200 毫克阿立哌唑后出现了 EPS。幸运的是,服用比哌立登后她的症状有所改善,并在服药五天后出院。本病例强调了阿立哌唑即使在其治疗指数范围内,也有可能导致严重后果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Case Reports in Medicine
Case Reports in Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
1.70
自引率
0.00%
发文量
53
审稿时长
13 weeks
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