Human Strongyloides stercoralis infection

Abstract

is an important soil-transmitted helminth occurring world-wide and affecting 30–100 million people. Because many cases are asymptomatic and sensitive diagnostic methods are lacking, infection is frequently underdiagnosed. The increasing incidence of autoimmune and wasting diseases and increased use of immunosuppressive agents, as well as the increased use of immunosuppressants and cytotoxic drugs, have increased infection and their mortality. This review provides information about epidemiology, life cycle, aetiology, pathology, comorbidities, immunology, vaccines, diagnosis, treatment, prevention, control and makes some recommendations for future prevention and control of this important parasite.