{"title":"Synthesis of 3-(2,3,5,6-tetrafluoropyridinylthio)pyrazoles from 3-aminopyrazoles","authors":"Denis S. Koltun, Alexander D. Dilman","doi":"10.1016/j.mencom.2024.06.020","DOIUrl":null,"url":null,"abstract":"<div><p>Pyrazoles bearing (2,3,5,6-tetrafluoropyridinyl)thio group were obtained from 3-aminopyrazoles. The reaction is performed by diazotization of starting amines followed by treatment of the intermediate diazonium salts with 2,3,5,6-tetrafluoropyridine-4-thiol and potassium carbonate. The method is best applied towards 4-substituted 3-aminopyrazoles.</p></div>","PeriodicalId":18542,"journal":{"name":"Mendeleev Communications","volume":"34 4","pages":"Pages 531-532"},"PeriodicalIF":1.8000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Mendeleev Communications","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0959943624001974","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Pyrazoles bearing (2,3,5,6-tetrafluoropyridinyl)thio group were obtained from 3-aminopyrazoles. The reaction is performed by diazotization of starting amines followed by treatment of the intermediate diazonium salts with 2,3,5,6-tetrafluoropyridine-4-thiol and potassium carbonate. The method is best applied towards 4-substituted 3-aminopyrazoles.
期刊介绍:
Mendeleev Communications is the journal of the Russian Academy of Sciences, launched jointly by the Academy of Sciences of the USSR and the Royal Society of Chemistry (United Kingdom) in 1991. Starting from 1st January 2007, Elsevier is the new publishing partner of Mendeleev Communications.
Mendeleev Communications publishes short communications in chemistry. The journal primarily features papers from the Russian Federation and the other states of the former USSR. However, it also includes papers by authors from other parts of the world. Mendeleev Communications is not a translated journal, but instead is published directly in English. The International Editorial Board is composed of eminent scientists who provide advice on refereeing policy.