Hybrid Polyvinyl Alcohol-Silica Antibacterial Nanofiber Fabricated by Combined Sol-Gel and Electrospinning Techniques

IF 2.3 4区材料科学 Q2 MATERIALS SCIENCE, CERAMICS

Journal of Sol-Gel Science and Technology Pub Date : 2024-08-11 DOI:10.1007/s10971-024-06510-w

Khadija El Kalaaoui, Aicha Boukhriss, Oumaima Bili, Mohamed Ait Chaoui, Sanaa Majid, Mohamed El Hajaji, Said Gmouh

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Abstract

Organic-inorganic hybrids are valuable due to their combined properties. This study fabricated polymer-silica hybrid nanofibers with antibacterial properties using silica and polyvinyl alcohol (PVA) through sol-gel and electrospinning methods. The nanofibers, incorporating chloropropyltriethoxysilane (CPTS) and Benzalkonium chloride (BAC), were analyzed for their morphology, chemical composition, mechanical properties, thermal properties, and antibacterial activity. Optimal characteristics in fibrous structure, mechanical strength, and antibacterial efficiency were achieved with a blended 8% wt PVA. Sample H, containing 1% BAC, showed significant bacterial growth inhibition (20 mm for Staphylococcus aureus and 9.2 mm for Escherichia coli), along with enhanced thermal stability (260.41 °C) and tensile strength (12.4 MPa). This study demonstrates the potential of electrospinning in creating advanced hybrid nanofibers with diverse applications in the medical field.

Graphical Abstract

Abstract Image

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通过溶胶-凝胶和电纺丝联合技术制备的聚乙烯醇-二氧化硅混合抗菌纳米纤维

有机-无机杂化物因其综合特性而具有重要价值。本研究利用二氧化硅和聚乙烯醇（PVA），通过溶胶-凝胶法和电纺丝法制备了具有抗菌性能的聚合物-二氧化硅杂化纳米纤维。研究分析了加入氯丙基三乙氧基硅烷（CPTS）和苯扎氯铵（BAC）的纳米纤维的形态、化学成分、机械性能、热性能和抗菌活性。8% 重量百分比的 PVA 混合物在纤维结构、机械强度和抗菌效率方面都达到了最佳特性。含有 1% BAC 的样品 H 显示出明显的细菌生长抑制效果（金黄色葡萄球菌抑制 20 mm，大肠杆菌抑制 9.2 mm），同时热稳定性（260.41 °C）和拉伸强度（12.4 MPa）也有所提高。这项研究证明了电纺丝技术在制造先进的混合纳米纤维方面的潜力，这种纤维在医疗领域有多种应用。

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来源期刊

Journal of Sol-Gel Science and Technology 工程技术-材料科学：硅酸盐

CiteScore

4.70

自引率

4.00%

发文量

280

审稿时长

2.1 months

期刊介绍： The primary objective of the Journal of Sol-Gel Science and Technology (JSST), the official journal of the International Sol-Gel Society, is to provide an international forum for the dissemination of scientific, technological, and general knowledge about materials processed by chemical nanotechnologies known as the "sol-gel" process. The materials of interest include gels, gel-derived glasses, ceramics in form of nano- and micro-powders, bulk, fibres, thin films and coatings as well as more recent materials such as hybrid organic-inorganic materials and composites. Such materials exhibit a wide range of optical, electronic, magnetic, chemical, environmental, and biomedical properties and functionalities. Methods for producing sol-gel-derived materials and the industrial uses of these materials are also of great interest.