SITH: An SiPM Readout ASIC for Prompt Gamma-Ray Detection in Hadrontherapy Applications

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
I. D’Adda;C. Riboldi;A. Saporito;G. Borghi;M. Carminati;C. Fiorini
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Abstract

We present the design and experimental characterization of spectroscopy imaging timing hadrontherapy (SITH) ASIC, a custom-designed integrated circuit (IC) 16-channel ASIC for the readout of arrays of silicon photomultipliers (SiPMs) coupled to pixelated scintillators. This IC measures both the energy and time-of-arrival (ToA) of the detected gamma photons, and it is tailored for the specific application of prompt gamma imaging (PGI) for particle range verification in hadrontherapy treatments. The SITH ASIC features a low input impedance ( $\lt 10~\Omega $ ), an input dynamic range close to 80 dB with a full-scale range of 5nC, multiple triggering logic (internal/external), power dissipation of 14 mW/ch, and the flexibility for being used with both pixelated and monolithic scintillation crystals. Moreover, the input stage of each channel can process high input currents (in the tens of milliampere range) and can be coupled to large-area photodetectors (up to tens of nanofarad). The coincidence resolving time (CRT) of annihilation events measured with $3\times 3$ mm2 SiPMs coupled with $3\times 3\times 5$ mm3 LYSO scintillators is close to 200-ps FWHM. The reported experimental measurements were conducted with a 16-channel prototype of a prompt gamma-ray detection module, which provides a real-time measurement of the gamma-ray hit position, energy, and ToA through 16 time-to-digital converters (TDCs) implemented in FPGA. The maximum count rate per channel is approximately 3 Mc/s.
SITH:用于强放射治疗应用中伽马射线快速检测的 SiPM 读出 ASIC
我们介绍了光谱成像定时放射治疗(SITH)ASIC 的设计和实验特性,这是一种定制设计的 16 通道集成电路 (IC),用于读出与像素化闪烁体耦合的硅光电倍增管 (SiPM) 阵列。该集成电路可测量检测到的伽马光子的能量和到达时间(ToA),它是为瞬时伽马成像(PGI)的特定应用而量身定制的,可用于对放射治疗中的粒子范围进行验证。SITH ASIC 的特点是输入阻抗低(10~/Omega $),输入动态范围接近 80 dB,满量程范围为 5nC,具有多种触发逻辑(内部/外部),功率耗散为 14 mW/ch,可灵活地与像素化闪烁晶体和单片闪烁晶体一起使用。此外,每个通道的输入级都能处理高输入电流(数十毫安范围),并可与大面积光电探测器(高达数十纳法)耦合。使用与 3/3/3/5mm3 LYSO 闪烁器耦合的 3/3/3mm2 SiPM 测量的湮灭事件的重合分辨时间(CRT)接近 200 ps FWHM。报告中的实验测量是通过一个 16 通道的伽马射线瞬时探测模块原型进行的,该模块通过 FPGA 实现的 16 个时间-数字转换器(TDC)提供伽马射线命中位置、能量和 ToA 的实时测量。每个通道的最大计数率约为 3 Mc/s。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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