Sample size calculation for the sequential parallel comparison design with binary endpoint using exact methods

IF 1.2 4区数学 Q2 STATISTICS & PROBABILITY

Journal of Applied Statistics Pub Date : 2024-07-31 DOI:10.1080/02664763.2024.2385997

Guogen Shan, Yahui Zhang

引用次数: 0

Abstract

High placebo responses in clinical trial could reduce the treatment effect leading to the failure of a promising drug. Several strategies have been developed to minimize high placebo responses, inc...

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用精确法计算二元终点顺序平行比较设计的样本量

临床试验中的高安慰剂反应可能会降低治疗效果，导致有前途的药物失败。为了最大限度地减少高安慰剂反应，已经开发出了几种策略，包括...

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来源期刊

Journal of Applied Statistics 数学-统计学与概率论

CiteScore

3.40

自引率

0.00%

发文量

126

审稿时长

6 months

期刊介绍： Journal of Applied Statistics provides a forum for communication between both applied statisticians and users of applied statistical techniques across a wide range of disciplines. These areas include business, computing, economics, ecology, education, management, medicine, operational research and sociology, but papers from other areas are also considered. The editorial policy is to publish rigorous but clear and accessible papers on applied techniques. Purely theoretical papers are avoided but those on theoretical developments which clearly demonstrate significant applied potential are welcomed. Each paper is submitted to at least two independent referees.