Jessica White , Laura Mahady , Shameer Rafee , Michael Hutchinson , Sean O'Riordan , Fiadhnait O'Keeffe , Patricia Gough
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引用次数: 0
Abstract
Background
Although historically considered a motor disorder, cervical dystonia (CD) may present with subtle cognitive impairments. Basal ganglia dysfunction in other neurological conditions can lead to language impairments. Language in people with CD (pwCD) remains unexplored.
Objectives
The study aimed to explore phonological, grammatical, and semantic language abilities in pwCD compared to healthy controls.
Methods
19 pwCD and 20 control participants completed the Object and Colour subtests of the Rapid Automized Naming Task (RAN), the Test for Reception of Grammar-2 (TROG-2), and a lexical decision task with a masked priming paradigm that compared reaction times to words varying according to two factors-hand relatedness (hand-related, non-hand-related) and word category (verb, noun).
Results
Compared to controls, pwCD were less accurate at grammatical comprehension on the TROG-2 (p < 0.05, n2 = 0.15). There were no significant differences between pwCD and controls in phonological retrieval, as measured by the RAN. PwCD demonstrated an overall reduced priming effect for all words, however, there is some evidence in our data that this may be more pronounced for hand-related words.
Conclusion
Language deficits should be considered an area of future research in pwCD. These findings support the role of the motor system in language.
期刊介绍:
The Journal of Neurolinguistics is an international forum for the integration of the neurosciences and language sciences. JNL provides for rapid publication of novel, peer-reviewed research into the interaction between language, communication and brain processes. The focus is on rigorous studies of an empirical or theoretical nature and which make an original contribution to our knowledge about the involvement of the nervous system in communication and its breakdowns. Contributions from neurology, communication disorders, linguistics, neuropsychology and cognitive science in general are welcome. Published articles will typically address issues relating some aspect of language or speech function to its neurological substrates with clear theoretical import. Interdisciplinary work on any aspect of the biological foundations of language and its disorders resulting from brain damage is encouraged. Studies of normal subjects, with clear reference to brain functions, are appropriate. Group-studies on well defined samples and case studies with well documented lesion or nervous system dysfunction are acceptable. The journal is open to empirical reports and review articles. Special issues on aspects of the relation between language and the structure and function of the nervous system are also welcome.