Synthesis, characterization, and electrochemical uric acid sensing properties of Cu3N nanoparticles

IF 10.61 Q3 Biochemistry, Genetics and Molecular Biology

Biosensors and Bioelectronics: X Pub Date : 2024-07-31 DOI:10.1016/j.biosx.2024.100526

Munusamy Settu , Gnanamoorthy Govindhan , Bavani Thirugnanam , Kumar Kalpana , Majed A. Alotaibi

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Abstract

This article explores the development and applications of a Cu₃N/GCE-based sensor using differential pulse voltammetry (DPV) for selective uric acid (UA) detection in clinical analysis. The sensor achieves a limit of detection (LOD) of 2.57 × 10⁻⁸ M and a quantification limit (QL) of 8.102 × 10⁻⁸ M, demonstrating its capability to precisely quantify minute UA concentrations. With rapid responsiveness and reusability over 25 days, it offers cost-effective monitoring of UA levels, even in complex sample matrices. Cu₃N also exhibits high efficiency in degrading methylene blue (MB), achieving 87.7% degradation under optimized conditions, suggesting its potential as a photocatalyst for environmental remediation, particularly in dye degradation processes. Overall, Cu₃N-based technologies show promise in sensitive UA detection for clinical diagnostics, environmental remediation, and industrial catalysis, highlighting its versatility and broad applicability across scientific and practical domains.

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Cu3N 纳米粒子的合成、表征和电化学尿酸传感特性

本文探讨了基于 CuN/GCE 的传感器的开发和应用，该传感器采用差分脉冲伏安法 (DPV)，可在临床分析中选择性地检测尿酸 (UA)。该传感器的检测限 (LOD) 为 2.57 × 10 M，定量限 (QL) 为 8.102 × 10 M，证明了其精确定量微量尿酸浓度的能力。它反应迅速，可重复使用 25 天，即使在复杂的样品基质中也能经济高效地监测 UA 含量。CuN 还能高效降解亚甲基蓝 (MB)，在优化条件下可实现 87.7% 的降解，这表明它具有作为光催化剂进行环境修复的潜力，特别是在染料降解过程中。总之，基于 CuN 的技术在临床诊断、环境修复和工业催化的灵敏 UA 检测方面显示出前景，突出了它在科学和实用领域的多功能性和广泛适用性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biosensors and Bioelectronics: X Biochemistry, Genetics and Molecular Biology-Biophysics

CiteScore

4.60

自引率

0.00%

发文量

166

审稿时长

54 days

期刊介绍： Biosensors and Bioelectronics: X, an open-access companion journal of Biosensors and Bioelectronics, boasts a 2020 Impact Factor of 10.61 (Journal Citation Reports, Clarivate Analytics 2021). Offering authors the opportunity to share their innovative work freely and globally, Biosensors and Bioelectronics: X aims to be a timely and permanent source of information. The journal publishes original research papers, review articles, communications, editorial highlights, perspectives, opinions, and commentaries at the intersection of technological advancements and high-impact applications. Manuscripts submitted to Biosensors and Bioelectronics: X are assessed based on originality and innovation in technology development or applications, aligning with the journal's goal to cater to a broad audience interested in this dynamic field.