Box-Behnken design in optimization of the green liquid chromatographic method for the quantification of Afatinib in drug product: AQbD approach

IF 1 4区化学 Q4 BIOCHEMICAL RESEARCH METHODS

Journal of Liquid Chromatography & Related Technologies Pub Date : 2024-07-29 DOI:10.1080/10826076.2024.2384039

Pankaj Kisan Chatki, Mohanish Mohan Mirashe, Amol Sudhakar Warokar, Ujwala N. Mahajan

引用次数: 0

Abstract

The aim of this research work was to quantitatively determine the tyrosine kinase inhibitor, Afatinib, in tablets using an eco-friendly chromatographic method. The development of a green liquid chr...

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优化阿法替尼绿色液相色谱定量方法的盒式贝肯设计：AQbD方法

这项研究工作的目的是采用环保型色谱法定量测定片剂中的酪氨酸激酶抑制剂阿法替尼。该研究开发了一种绿色液相色谱法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Liquid Chromatography & Related Technologies 化学-分析化学

CiteScore

2.80

自引率

0.00%

发文量

审稿时长

4.9 months

期刊介绍： The Journal of Liquid Chromatography & Related Technologies is an internationally acclaimed forum for fast publication of critical, peer reviewed manuscripts dealing with analytical, preparative and process scale liquid chromatography and all of its related technologies, including TLC, capillary electrophoresis, capillary electrochromatography, supercritical fluid chromatography and extraction, field-flow technologies, affinity, and much more. New separation methodologies are added when they are developed. Papers dealing with research and development results, as well as critical reviews of important technologies, are published in the Journal.