Position-dependent effects of transcription factor binding

IF 39.1 1区生物学 Q1 GENETICS & HEREDITY

Nature Reviews Genetics Pub Date : 2024-08-12 DOI:10.1038/s41576-024-00769-z

Kirsty Minton

引用次数: 0

Abstract

Duttke et al. show that transcription factors have position-dependent effects relative to their distance from the transcription start site, which suggests that a ''spatial grammar'' could be used to encode multiple gene-regulatory programmes.

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转录因子结合的位置依赖效应

Duttke 等人的研究表明，转录因子与转录起始位点的距离会产生位置依赖性效应，这表明 "空间语法 "可用于编码多种基因调控程序。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Genetics 生物-遗传学

CiteScore

57.40

自引率

0.50%

发文量

113

审稿时长

6-12 weeks

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