Plant-derived exosome-like nanoparticles - from Laboratory to factory, a landscape of application, challenges and prospects.

IF 7.3 1区农林科学 Q1 FOOD SCIENCE & TECHNOLOGY

Critical reviews in food science and nutrition Pub Date : 2024-08-11 DOI:10.1080/10408398.2024.2388888

Chaozhi Wei, Mengyu Zhang, Jintao Cheng, Jinzhong Tian, Guiling Yang, Yuanxiang Jin

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引用次数: 0

Abstract

Recent decades have witnessed substantial interest in extracellular vesicles (EVs) due to their crucial role in intercellular communication across various biological processes. Among these, plant-derived exosome-like Nanoparticles (ELNs) have rapidly gained recognition as highly promising candidates. ELNs, characterized by diverse sources, cost-effective production, and straightforward isolation, present a viable option for preventing and treating numerous diseases. Furthermore, ELNs hold significant potential as carriers for natural or engineered drugs, enhancing their attractiveness and drawing considerable attention in science and medicine. However, translating ELNs into clinical applications poses several challenges. This study explores these challenges and offers critical insights into potential research directions. Additionally, it provides a forward-looking analysis of the industrial prospects for ELNs. With their broad applications and remarkable potential, ELNs stand at the forefront of biomedical innovation, poised to revolutionize disease management and drug delivery paradigms in the coming years.

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植物外泌体纳米颗粒--从实验室到工厂，应用、挑战和前景展望。

近几十年来，由于细胞外囊泡（EVs）在各种生物过程的细胞间通讯中发挥着至关重要的作用，人们对它们产生了浓厚的兴趣。其中，源自植物的类外泌体纳米颗粒（ELNs）作为极具潜力的候选物质已迅速获得认可。ELNs 具有来源多样、生产成本低、分离简单等特点，是预防和治疗多种疾病的可行选择。此外，ELNs 还具有作为天然药物或工程药物载体的巨大潜力，从而增强了其吸引力，并引起了科学和医学界的广泛关注。然而，将ELN转化为临床应用面临着一些挑战。本研究探讨了这些挑战，并对潜在的研究方向提出了重要见解。此外，它还对电子病历网络的产业前景进行了前瞻性分析。凭借其广泛的应用和巨大的潜力，ELN 站在了生物医学创新的前沿，有望在未来几年彻底改变疾病管理和药物输送模式。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Critical reviews in food science and nutrition 工程技术-食品科技

CiteScore

22.60

自引率

4.90%

发文量

600

审稿时长

7.5 months

期刊介绍： Critical Reviews in Food Science and Nutrition serves as an authoritative outlet for critical perspectives on contemporary technology, food science, and human nutrition. With a specific focus on issues of national significance, particularly for food scientists, nutritionists, and health professionals, the journal delves into nutrition, functional foods, food safety, and food science and technology. Research areas span diverse topics such as diet and disease, antioxidants, allergenicity, microbiological concerns, flavor chemistry, nutrient roles and bioavailability, pesticides, toxic chemicals and regulation, risk assessment, food safety, and emerging food products, ingredients, and technologies.