Investigation of the utility of smartphone-based gait analyses in discrimination between patients with Alzheimer's disease and Parkinson's disease.

IF 1.4 4区心理学 Q4 CLINICAL NEUROLOGY

Applied Neuropsychology-Adult Pub Date : 2024-08-08 DOI:10.1080/23279095.2024.2386369

Halil Onder, Ozlem Bizpinar

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引用次数: 0

Abstract

Objective: To reveal the discriminative value of gait parameters between Alzheimer's disease (AD) and Parkinson's disease (PD) subjects.

Methods: We included all consecutive patients with newly diagnosed AD and those with a diagnosis of PD who applied to our polyclinic between March 2022 and June 2022. The demographic and clinical features were evaluated during interviews. The gait analyses were performed using a quantitative, smartphone-based gait analyses program. Using this program, the step time (ST), step length (SL), step number (SN), gait velocity (GV), and cadence were measured in all individuals.

Results: Overall, 31 patients with AD and 45 with PD were enrolled in the analyses. The mean age of the AD group was higher according to those with PD. As expected, the Mini-Mental State Examination (MMSE) values were lower in the AD group. The comparative analyses of the gait parameters between groups did not reveal differences in any of the measures. The correlation analyses to investigate the possible association between the disease severity and gait parameters revealed that the MDS-UPDRS showed low negative correlations with SL and GV.

Conclusion: Our findings suggest that the evaluation of gait using the gait analyses program does not contribute to the discrimination between AD and PD in clinical practice.

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研究基于智能手机的步态分析在区分阿尔茨海默病患者和帕金森病患者方面的实用性。

目的揭示阿尔茨海默病（AD）和帕金森病（PD）患者步态参数的鉴别价值：我们纳入了 2022 年 3 月至 2022 年 6 月期间在本综合医院就诊的所有新诊断为阿尔茨海默病（AD）和帕金森病（PD）的连续患者。在访谈过程中对人口统计学和临床特征进行了评估。步态分析使用基于智能手机的定量步态分析程序进行。使用该程序测量了所有患者的步长（SL）、步幅（ST）、步数（SN）、步速（GV）和步调：共有 31 名注意力缺失症患者和 45 名注意力缺失症患者参与分析。注意力缺失症患者的平均年龄高于帕金森病患者。不出所料，注意力缺失症组的迷你精神状态检查（MMSE）值较低。对各组步态参数的比较分析未发现任何差异。为研究疾病严重程度与步态参数之间可能存在的关联而进行的相关性分析表明，MDS-UPDRS与SL和GV呈低负相关：我们的研究结果表明，在临床实践中，使用步态分析程序对步态进行评估无助于区分注意力缺失症和帕金森病。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Applied Neuropsychology-Adult CLINICAL NEUROLOGY-PSYCHOLOGY

CiteScore

4.50

自引率

11.80%

发文量

134

期刊介绍： pplied Neuropsychology-Adult publishes clinical neuropsychological articles concerning assessment, brain functioning and neuroimaging, neuropsychological treatment, and rehabilitation in adults. Full-length articles and brief communications are included. Case studies of adult patients carefully assessing the nature, course, or treatment of clinical neuropsychological dysfunctions in the context of scientific literature, are suitable. Review manuscripts addressing critical issues are encouraged. Preference is given to papers of clinical relevance to others in the field. All submitted manuscripts are subject to initial appraisal by the Editor-in-Chief, and, if found suitable for further considerations are peer reviewed by independent, anonymous expert referees. All peer review is single-blind and submission is online via ScholarOne Manuscripts.