Meibography health score: a simple grading system for isotretinoin-induced meibography alterations on patients with acne vulgaris.

IF 1.1 4区医学 Q3 OPHTHALMOLOGY

Arquivos brasileiros de oftalmologia Pub Date : 2024-08-02 eCollection Date: 2024-01-01 DOI:10.5935/0004-2749.2023-0150

Fabio Mendonça Xavier Andrade, Flavio Hirai, Tais Hitomi Wakamatsu, Rebecca Ignacio Subira Medina, Denise de Freitas

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引用次数: 0

Abstract

Purpose: To develop a simple, subjective, and reliable grading scale for isotretinoin-induced meibography changes.

Methods: After analyzing meibography images obtained from systemic isotretinoin users, a grading scale was proposed and named "meibography health score." The score ranged from 1 to 3, with decreasing gland reflectivity and identifiable margins. A total of 11 medical professionals were asked to grade 10 meibography images obtained from isotretinoin users using the proposed scale and were divided into three groups: (A) ophthalmologists with experience with meibography, (B) ophthalmologists with no experience with meibography, and (C) radiologists. The kappa statistic was determined to test interrater reliability.

Results: The overall kappa was approximately 0.64. The kappa scores for Groups A, B, and C were 0.78, 0.59, and 0.90, respectively. Grade 2 had the lowest kappa scores (0.62, 0.35, and 0.82 for A, B, and C, respectively) and grade 3 the highest (0.78, 0.90, and 1.0 for A, B and C, respectively). Furthermore, Group C had the highest kappa scores and Group B the lowest.

Conclusion: The meibography health score exhibited good interrater reliability, particularly in severe cases.

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甲胎蛋白造影健康评分：异维A酸引起的寻常型痤疮患者甲胎蛋白造影改变的简单分级系统。

目的：针对异维A酸引起的眼睑纹理变化，制定一个简单、主观、可靠的分级表：方法：在分析了从全身使用异维A酸的患者处获得的肉眼可见光图像后，提出了一个分级表，并命名为 "肉眼可见光健康评分"。分值从 1 到 3 不等，腺体反射率和可识别的边缘都在下降。共有 11 名专业医务人员被要求使用建议的量表对从异维A酸使用者处获得的 10 张水肿图像进行评分，并被分为三组：(A) 有水肿成像经验的眼科医生，(B) 没有水肿成像经验的眼科医生，以及 (C) 放射科医生。测定卡帕统计量来检验检查者之间的可靠性：总体卡帕值约为 0.64。A 组、B 组和 C 组的卡方评分分别为 0.78、0.59 和 0.90。第二级的 kappa 分数最低（A、B 和 C 组分别为 0.62、0.35 和 0.82），第三级最高（A、B 和 C 组分别为 0.78、0.90 和 1.0）。此外，C 组的卡方评分最高，B 组最低：结论：甲胎蛋白造影健康评分显示出良好的交互可靠性，尤其是在严重病例中。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Arquivos brasileiros de oftalmologia OPHTHALMOLOGY-

CiteScore

1.60

自引率

0.00%

发文量

200

审稿时长

6-12 weeks

期刊介绍： The ABO-ARQUIVOS BRASILEIROS DE OFTALMOLOGIA (ABO, ISSN 0004-2749 - print and ISSN 1678-2925 - (ABO, ISSN 0004-2749 - print and ISSN 1678-2925 - electronic version), the official bimonthly publication of the Brazilian Council of Ophthalmology (CBO), aims to disseminate scientific studies in Ophthalmology, Visual Science and Health public, by promoting research, improvement and updating of professionals related to the field.