RETRACTION: Capn4 is a Marker of Poor Clinical Outcomes and Promotes Nasopharyngeal Carcinoma Metastasis via Nuclear Factor-κB-Induced Matrix Metalloproteinase 2 Expression

IF 4.5 2区医学 Q1 ONCOLOGY

Cancer Science Pub Date : 2024-08-05 DOI:10.1111/cas.16305

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引用次数: 0

Abstract

RETRACTION: P.-C. Zheng, X. Chen, H.-W. Zhu, W. Zheng, L.-H. Mao, C. Lin, J.-N. Liu and M. Zheng, “Capn4 is a Marker of Poor Clinical Outcomes and Promotes Nasopharyngeal Carcinoma Metastasis via Nuclear Factor-κB-Induced Matrix Metalloproteinase 2 Expression,” Cancer Science 105, no. 6 (2014): 630–638, https://doi.org/10.1111/cas.12416.

The above article, published online on 07 April 2014 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Masanori Hatakeyama; Japanese Cancer Association; and John Wiley & Sons Australia, Ltd. Following publication, concerns were raised by a third party regarding suspected overlap of elements within the western blot presented in Figure 3b and a figure published earlier in another paper elsewhere. Furthermore, image analysis uncovered several instances of overlap within the cell migration and cell invasion Transwell assay images presented in Figure 3c. The authors were unable to provide the original data and did not provide a satisfactory explanation for the overlaps. As a result, the article's conclusions can no longer be considered valid.

查看原文本刊更多论文

回放：Capn4是临床疗效不佳的标志物，并通过核因子κB诱导基质金属蛋白酶2的表达促进鼻咽癌转移。

撤回：P.-C. Zheng, X. Chen, H.-W.Zheng, X. Chen, H.-W. Zhu, W. Zheng, L.-H.Zhu, W. Zheng, L.-H. Mao, C. Lin, J.-N.Mao, C. Lin, J.-N. Liu and M. Zheng, "Capn4 is a Marker Poor Clinical Outcomes.Liu和M. Zheng, "Capn4 is a Marker of Poor Clinical Outcomes and Promotes Nasopharyngeal Carcinoma Metastasis via Nuclear Factor-κB-Induced Matrix Metalloproteinase 2 Expression," Cancer Science 105, no：630-638, https://doi.org/10.1111/cas.12416.上述文章于 2014 年 4 月 7 日在线发表于 Wiley Online Library (wileyonlinelibrary.com)，经杂志主编 Masanori Hatakeyama、日本癌症协会和 John Wiley & Sons Australia, Ltd.同意，已被撤回。文章发表后，有第三方对图 3b 中的 Western 印迹与早些时候发表在其他地方的另一篇论文中的图中的元素疑似重叠提出了质疑。此外，图像分析还发现图 3c 中的细胞迁移和细胞侵袭 Transwell 试验图像中有多处重叠。作者无法提供原始数据，也没有对重叠现象做出令人满意的解释。因此，文章的结论不再有效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cancer Science 医学-肿瘤学

自引率

3.50%

发文量

406

审稿时长

2 months

期刊介绍： Cancer Science (formerly Japanese Journal of Cancer Research) is a monthly publication of the Japanese Cancer Association. First published in 1907, the Journal continues to publish original articles, editorials, and letters to the editor, describing original research in the fields of basic, translational and clinical cancer research. The Journal also accepts reports and case reports. Cancer Science aims to present highly significant and timely findings that have a significant clinical impact on oncologists or that may alter the disease concept of a tumor. The Journal will not publish case reports that describe a rare tumor or condition without new findings to be added to previous reports; combination of different tumors without new suggestive findings for oncological research; remarkable effect of already known treatments without suggestive data to explain the exceptional result. Review articles may also be published.