{"title":"DMP-1 expression in alveolar bone socket following <i>Anredera cordifolia</i> (Ten.) Steenis treatment: A histological study.","authors":"Christian Khoswanto, Ira Kusuma Dewi","doi":"10.5455/javar.2024.k775","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>The study aimed to ascertain how <i>Anredera cordifolia</i> (Ten.) Steenis Gel affects the expression of protein dentin matrix protein-1 (DMP-1) in alveolar Wistar rats after tooth extraction.</p><p><strong>Materials and methods: </strong>Rats were given <i>A. cordifolia</i> (Ten.) Steenis gel was in the socket after tooth extraction, and then the wound was sutured. The rats were sacrificed for 8 and 15 days following tooth extraction. The results on the 8<sup>th</sup> and 15<sup>th</sup> days demonstrate that the expression of DMP-1 in the treatment group is significantly higher than in the control group.</p><p><strong>Results: </strong>Expression of DMP-1 in the socket after tooth extraction on days 8 and 15 with a 400x magnification light microscope in both of the <i>A. cordifolia</i> (Ten.) Steenis gel treatment groups showed significant differences compared to the control group.</p><p><strong>Conclusion: </strong>The use of <i>A. cordifolia</i> (Ten.) Steenis gel can stimulate DMP-1 expression in alveolar bone after tooth extraction.</p>","PeriodicalId":14892,"journal":{"name":"Journal of Advanced Veterinary and Animal Research","volume":"11 2","pages":"291-295"},"PeriodicalIF":1.5000,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11296160/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Advanced Veterinary and Animal Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5455/javar.2024.k775","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/6/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"AGRICULTURE, DAIRY & ANIMAL SCIENCE","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: The study aimed to ascertain how Anredera cordifolia (Ten.) Steenis Gel affects the expression of protein dentin matrix protein-1 (DMP-1) in alveolar Wistar rats after tooth extraction.
Materials and methods: Rats were given A. cordifolia (Ten.) Steenis gel was in the socket after tooth extraction, and then the wound was sutured. The rats were sacrificed for 8 and 15 days following tooth extraction. The results on the 8th and 15th days demonstrate that the expression of DMP-1 in the treatment group is significantly higher than in the control group.
Results: Expression of DMP-1 in the socket after tooth extraction on days 8 and 15 with a 400x magnification light microscope in both of the A. cordifolia (Ten.) Steenis gel treatment groups showed significant differences compared to the control group.
Conclusion: The use of A. cordifolia (Ten.) Steenis gel can stimulate DMP-1 expression in alveolar bone after tooth extraction.