Impact of patent foramen ovale with left-to-right shunt on atrial fibrillation ablation in young patients.

IF 1.4 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Indian heart journal Pub Date : 2024-08-02 DOI:10.1016/j.ihj.2024.07.010

Tao Wang, Xinyang Jin, Yalin Lu, Xuemei Qi, Chen Chen, Jian Yang, Qingxiong Yue, Shijun Li

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引用次数: 0

Abstract

Objective: The CABANA study shows that atrial fibrillation (AF) paitents younger than 65 years benefit more from the AF radiofrequency catheter ablation (RFCA) procedure. The aim of this study is to investigate the impact of inherent patent foramen ovale (PFO) with a Left-to-Right Shunt on the RFCA procedure in young AF patients.

Methods: Based on the presence or absence of inherent PFO, the AF patients were divided into the PFO groups and the non-PFO group. Clinical follow-up was also investigated.

Results: A total of 285 AF patients were enrolled. PFO was detected by TEE in 42 patients. The age of patients at initial AF onset was younger in the PFO group than in the non-PFO group (58.3 ± 8.9 vs. 62.3 ± 9.6 years, P = 0.012). There were more AF patients aged <55 years in the PFO group than in the non-PFO group. For the 9 AF patients with PFO who experienced AF recurrence and the left-to-right shunts decreased in size in 5 of the patients aged <65 years. The LAD decreased in those patients. In the PeAF patients, 53/64 patients aged <65 years and 23/40 patients aged older than 65 years were free of AF (82.8 % vs. 57.5 %, respectively; P = 0.005).

Conclusion: Success is not affected when AF is combined PFO compared with AF without PFO. Young patients have better PeAF RFCA outcomes. AF in young patients with left atria enlargement and a serious AF burden, may lead to reduced EF and render PFO easy to detect.

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伴有左向右分流的卵圆孔未闭对年轻患者心房颤动消融术的影响。

研究目的CABANA 研究显示，65 岁以下的房颤患者从房颤射频导管消融术（RFCA）中获益更多。本研究旨在探讨具有左向右分流的固有卵圆孔孔（PFO）对年轻房颤患者进行射频导管消融术的影响：根据是否存在先天性 PFO，将房颤患者分为 PFO 组和非 PFO 组。方法：根据是否存在先天性 PFO，将房颤患者分为 PFO 组和非 PFO 组，并对临床随访情况进行调查：共有 285 名房颤患者入选。结果：共纳入 285 例房颤患者，其中 42 例患者通过 TEE 检测出 PFO。与非 PFO 组相比，PFO 组房颤患者初次发病时的年龄更小（58.3 ± 8.9 岁 vs. 62.3 ± 9.6 岁，P = 0.012）。心房颤动患者的年龄更大结论：合并心房颤动时，成功率不受影响：与无 PFO 的房颤相比，合并 PFO 的房颤不会影响成功率。年轻患者的 PeAF RFCA 成功率更高。年轻心房颤动患者左心房增大，心房颤动负担严重，可能导致 EF 值降低，使 PFO 容易被发现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian heart journal CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

2.60

自引率

6.70%

发文量

审稿时长

52 days

期刊介绍： Indian Heart Journal (IHJ) is the official peer-reviewed open access journal of Cardiological Society of India and accepts articles for publication from across the globe. The journal aims to promote high quality research and serve as a platform for dissemination of scientific information in cardiology with particular focus on South Asia. The journal aims to publish cutting edge research in the field of clinical as well as non-clinical cardiology - including cardiovascular medicine and surgery. Some of the topics covered are Heart Failure, Coronary Artery Disease, Hypertension, Interventional Cardiology, Cardiac Surgery, Valvular Heart Disease, Pulmonary Hypertension and Infective Endocarditis. IHJ open access invites original research articles, research briefs, perspective, case reports, case vignette, cardiovascular images, cardiovascular graphics, research letters, correspondence, reader forum, and interesting photographs, for publication. IHJ open access also publishes theme-based special issues and abstracts of papers presented at the annual conference of the Cardiological Society of India.

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