A narrative review of the literature: The role of biologics and JAK inhibitors in vitiligo

IF 2.2 4区医学 Q2 DERMATOLOGY

Australasian Journal of Dermatology Pub Date : 2024-08-01 DOI:10.1111/ajd.14353

Rhiannon Russell MD, Benjamin S. Daniel MBBS

引用次数: 0

Abstract

Vitiligo is a chronic depigmenting disorder that significantly impacts the quality of life of patients. Though there have been significant advancements in targeted therapies in skin diseases such as psoriasis or eczema, the progress in the treatment of vitiligo has been slow, with minimal studies assessing the effect of biologics, though there has been recent evidence of the effectiveness of JAK inhibition. This paper reviews the published case reports and studies for the use of systemic targeted therapies including biologics and JAK inhibitors in vitiligo.

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文献综述：生物制剂和JAK抑制剂在白癜风中的作用。

白癜风是一种慢性脱色性疾病，严重影响患者的生活质量。虽然银屑病或湿疹等皮肤病的靶向治疗取得了重大进展，但白癜风的治疗进展缓慢，评估生物制剂疗效的研究极少，不过最近有证据表明JAK抑制剂具有疗效。本文回顾了已发表的病例报告和关于系统性靶向疗法（包括生物制剂和JAK抑制剂）在白癜风中应用的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Australasian Journal of Dermatology 医学-皮肤病学

CiteScore

3.20

自引率

5.00%

发文量

186

审稿时长

6-12 weeks

期刊介绍： Australasian Journal of Dermatology is the official journal of the Australasian College of Dermatologists and the New Zealand Dermatological Society, publishing peer-reviewed, original research articles, reviews and case reports dealing with all aspects of clinical practice and research in dermatology. Clinical presentations, medical and physical therapies and investigations, including dermatopathology and mycology, are covered. Short articles may be published under the headings ‘Signs, Syndromes and Diagnoses’, ‘Dermatopathology Presentation’, ‘Vignettes in Contact Dermatology’, ‘Surgery Corner’ or ‘Letters to the Editor’.