The progress and future of corneal endothelial transplantation.

IF 2.1 3区 医学 Q2 OPHTHALMOLOGY
Japanese Journal of Ophthalmology Pub Date : 2024-09-01 Epub Date: 2024-07-31 DOI:10.1007/s10384-024-01083-1
Toshiki Shimizu, Satoru Yamagami, Takahiko Hayashi
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引用次数: 0

Abstract

Endothelial transplantation has recently been accepted worldwide, in the long history of corneal transplantation. The introduction of endothelial keratoplasty (Descemet stripping automated endothelial keratoplasty and Descemet membrane endothelial keratoplasty) has enabled us to expand the surgical indications owing to the low incidence of rejection and quick recovery of visual function. New technologies have been developed to ensure stable postoperative outcomes with a shorter learning curve, such as transplantation using cultured human endothelial cells and induced pluripotent stem cells (iPS) or new devices such as artificial endothelium. This review discusses the history and characteristics of corneal transplantation alongside new treatment options that may offer hope for patients with endothelial disease in the future.

Abstract Image

角膜内皮移植的进展与未来。
在角膜移植的悠久历史中,内皮移植近来已为全世界所接受。内皮角膜移植术(Descemet 剥离自动内皮角膜移植术和 Descemet 膜内皮角膜移植术)因其排斥反应发生率低、视功能恢复快而使我们得以扩大手术适应症。为了确保术后效果稳定,缩短学习曲线,我们开发了一些新技术,如使用培养的人类内皮细胞和诱导多能干细胞(iPS)进行移植,或使用人工内皮等新设备。本综述将讨论角膜移植的历史和特点,以及未来可能为内皮疾病患者带来希望的新治疗方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
4.80
自引率
8.30%
发文量
65
审稿时长
6-12 weeks
期刊介绍: The Japanese Journal of Ophthalmology (JJO) was inaugurated in 1957 as a quarterly journal published in English by the Ophthalmology Department of the University of Tokyo, with the aim of disseminating the achievements of Japanese ophthalmologists worldwide. JJO remains the only Japanese ophthalmology journal published in English. In 1997, the Japanese Ophthalmological Society assumed the responsibility for publishing the Japanese Journal of Ophthalmology as its official English-language publication. Currently the journal is published bimonthly and accepts papers from authors worldwide. JJO has become an international interdisciplinary forum for the publication of basic science and clinical research papers.
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