Lifestyle Intervention in Reducing Insulin Resistance and Preventing type 2 Diabetes in Asia Pacific Region: A Systematic Review and Meta-Analysis.

IF 5.2 2区医学 Q1 ENDOCRINOLOGY & METABOLISM

Current Diabetes Reports Pub Date : 2024-09-01 Epub Date: 2024-07-31 DOI:10.1007/s11892-024-01548-0

Yingting Cao, Abha Shrestha, Amy Janiczak, Xia Li, Yang Lu, Tilahun Haregu

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Abstract

Purpose of review: To update the evidence of lifestyle interventions for the prevention of type 2 diabetes mellites (T2DM) in adults, particularly in the Asia Pacific region. The key questions to ask are: 1) How effective are lifestyle interventions in preventing T2DM among at-risk adults in the Asia Pacific Region? 2)What are the key characteristics of the implementation of lifestyle interventions for diabetes prevention?

Recent findings: Lifestyle interventions for the prevention of T2DM have been suggested to be effective. There is evidence of ethnic differences in some glycaemic and anthropometric outcomes. The meta-analysis suggested a significant result in reducing waist circumference (standardised mean difference - 019, 95%CI ( -0.31, -0.06)), and no significant effects in other outcomes. However, the implementation outcomes suggested lifestyle intervention might be a cost-effective and sustainable approach in T2DM particularly in countries in the Asia Pacific Region. The focus of lifestyle intervention in the Asia Pacific Region should not only lie in the effectiveness of the trial but a thorough evaluation of the implementation outcomes, as well as cultural adaptations, with the support of all stakeholders through all stages of the implementation.

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亚太地区减少胰岛素抵抗和预防 2 型糖尿病的生活方式干预：系统回顾与元分析》。

综述目的：更新生活方式干预预防成人 2 型糖尿病（T2DM）的证据，尤其是在亚太地区。关键问题是1）生活方式干预对亚太地区高危成人预防 T2DM 的效果如何？2）实施生活方式干预预防糖尿病的主要特点是什么？预防 T2DM 的生活方式干预被认为是有效的。有证据表明，某些血糖和人体测量结果存在种族差异。荟萃分析表明，生活方式干预在减少腰围方面有显著效果（标准化平均差-019，95%CI ( -0.31, -0.06)），而在其他方面没有显著效果。然而，实施结果表明，生活方式干预可能是治疗 T2DM 的一种具有成本效益且可持续的方法，尤其是在亚太地区国家。亚太地区生活方式干预的重点不应仅在于试验的有效性，而应在所有利益相关者的支持下，在实施的各个阶段对实施结果以及文化适应性进行全面评估。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Diabetes Reports 医学 -

CiteScore

9.80

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The goal of this journal is to publish cutting-edge reviews on subjects pertinent to all aspects of diabetes epidemiology, pathophysiology, and management. We aim to provide incisive, insightful, and balanced contributions from leading experts in each relevant domain that will be of immediate interest to a wide readership of clinicians, basic scientists, and translational investigators. We accomplish this aim by appointing major authorities to serve as Section Editors in key subject areas across the discipline. Section Editors select topics to be reviewed by leading experts who emphasize recent developments and highlight important papers published over the past year on their topics, in a crisp and readable format. We also provide commentaries from well-known figures in the field, and an Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research.