Leydig-Sertoli collision sex-cord stromal tumor of the testis: a case report of an unusual entity

Diagnostic Histopathology Pub Date : 2024-07-20 DOI:10.1016/j.mpdhp.2024.07.007

Ludovica Pepe , Vincenzo Fiorentino , Cristina Pizzimenti, Antonio Ieni, Maria Lentini, Giovanni Tuccari, Guido Fadda, Vincenzo Ficarra, Maurizio Martini

引用次数: 0

Abstract

Testicular tumors are extremely rare, representing 1–1.5% of all neoplasms in men, and sex cord-stromal tumors account for about 5% of them. Histopathological diagnosis of such entities poses several challenges, mainly related to the fact that they can present in mixed forms and that immunohistochemical analyses can only be of partial help. We herein report a unique case of a collision sex cord-stromal tumor and discuss all the challenges faced in the diagnosis of such an entity. An accurate morphological examination of the entire lesion and a suitable immunohistochemical panel are essential for a correct diagnosis.

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睾丸莱德-塞尔托利碰撞性索间质瘤：一个不寻常实体的病例报告

睾丸肿瘤极为罕见，占男性肿瘤总数的 1-1.5%，其中性索间质瘤约占 5%。此类肿瘤的组织病理学诊断存在诸多挑战，主要是因为它们可能以混合形式出现，而免疫组化分析只能提供部分帮助。我们在此报告了一例独特的碰撞性索间质瘤，并讨论了诊断此类肿瘤所面临的所有挑战。对整个病变进行准确的形态学检查和合适的免疫组化分析对于正确诊断至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diagnostic Histopathology Medicine-Pathology and Forensic Medicine

CiteScore

1.30

自引率

0.00%

发文量

期刊介绍： This monthly review journal aims to provide the practising diagnostic pathologist and trainee pathologist with up-to-date reviews on histopathology and cytology and related technical advances. Each issue contains invited articles on a variety of topics from experts in the field and includes a mini-symposium exploring one subject in greater depth. Articles consist of system-based, disease-based reviews and advances in technology. They update the readers on day-to-day diagnostic work and keep them informed of important new developments. An additional feature is the short section devoted to hypotheses; these have been refereed. There is also a correspondence section.