Piceatannol, a comprehensive review of health perspectives and pharmacological aspects

IF 5.3 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Arabian Journal of Chemistry Pub Date : 2024-07-26 DOI:10.1016/j.arabjc.2024.105939

Hala I. Al-Jaber , Ashok K. Shakya , Mahmoud A. Al-Qudah , Lina M. Barhoumi , Hana E. Abu-Sal , Hazem S. Hasan , Nezar Al-Bataineh , Sultan Abu-Orabi , Mohammad S. Mubarak

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Abstract

Piceatannol, a natural polyphenolic stilbenoid found in numerous fruits and vegetables such as grapes, passionate fruit, blueberries, and white tea, is well recognized for its diverse pharmacological effects. Numerous previous research studies demonstrated the intriguing bioactivity of piceatannol, including its antioxidant, anti-inflammatory, and cancer preventive and neuroprotective properties. It has also shown potential benefits in managing hypercholesterolemia, atherosclerosis, angiogenesis, and cardiovascular diseases. Accordingly, this comprehensive review aims to provide an updated overview and covers the recent literature dealing with the chemistry of piceatannol, its bioavailability, pharmacological activities, and potential health benefits. In addition, the review will focus on the medicinal and traditional significance of piceatannol in combating various diseases and ailments.

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皮夏单宁，健康观点和药理方面的综合评述

皮卡丹宁醇是一种天然多酚类芪类化合物，存在于葡萄、西番莲果、蓝莓和白茶等多种水果和蔬菜中，因其多种药理作用而广受认可。以往的大量研究表明，皮卡丹宁醇具有耐人寻味的生物活性，包括抗氧化、抗炎、预防癌症和保护神经的特性。它在控制高胆固醇血症、动脉粥样硬化、血管生成和心血管疾病方面也显示出潜在的益处。因此，这篇综合综述旨在提供最新的概述，涵盖了有关皮卡丹酚化学性质、生物利用度、药理活性和潜在健康益处的最新文献。此外，该综述还将重点介绍皮夏单宁醇在防治各种疾病和病痛方面的药用和传统意义。

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来源期刊

Arabian Journal of Chemistry CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

10.80

自引率

3.30%

发文量

763

审稿时长

63 days

期刊介绍： The Arabian Journal of Chemistry is an English language, peer-reviewed scholarly publication in the area of chemistry. The Arabian Journal of Chemistry publishes original papers, reviews and short reports on, but not limited to: inorganic, physical, organic, analytical and biochemistry. The Arabian Journal of Chemistry is issued by the Arab Union of Chemists and is published by King Saud University together with the Saudi Chemical Society in collaboration with Elsevier and is edited by an international group of eminent researchers.