Yichuan Wu , Jiaqi Chen , Yuan Tao , Manlu Xiao , Jingrong Xiong , Aomiao Chen , Xiaoqin Ma , Linna Li , Hongxia Jia , Qian Zhang , Yaoming Xue , Yijie Jia , Zongji Zheng
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引用次数: 0
Abstract
Aims
This study aimed to investigate the association between dietary protein intake and mortality among patients with diabetic kidney disease.
Methods
The research encompassed a total of 2901 participants diagnosed with diabetic kidney disease, drawn from the National Health and Nutrition Examination Survey (NHANES). To determine outcomes related to all-cause and cardiovascular mortality, connections were established with the National Death Index up until December 31, 2019. Estimations of hazard ratios (HRs) and their corresponding 95 % confidence intervals (CIs) were conducted using Cox proportional hazard ratio models.
Results
During the 261,239 person-years of follow-up, 1236 deaths were recorded. After multivariate adjustment, the weighted hazard ratio (HR) and 95 % CIs for participants with 1.0–1.2 g/kg of protein intake was 0.65 (0.44, 0.96) for all-cause mortality. A higher proportion of animal protein intake was found to be associated with an increased mortality risk. Stratified analyses showed that higher protein intake benefited older participants.
Conclusions
In diabetic kidney disease patients, 1.0–1.2 g/kg of protein was associated with lower mortality and 0.6–1.2 g/kg of protein especially benefitted patients ≥60 years.
期刊介绍:
Diabetes and Metabolic Syndrome: Clinical Research and Reviews is the official journal of DiabetesIndia. It aims to provide a global platform for healthcare professionals, diabetes educators, and other stakeholders to submit their research on diabetes care.
Types of Publications:
Diabetes and Metabolic Syndrome: Clinical Research and Reviews publishes peer-reviewed original articles, reviews, short communications, case reports, letters to the Editor, and expert comments. Reviews and mini-reviews are particularly welcomed for areas within endocrinology undergoing rapid changes.