ICP-OES Analysis of Siddha Formulation Venkara Mathirai

Abstract

Background: The Venkara Mathirai(VM) is a herbomineral formulation used for treating ulcer, anaemia and Arthritis. Objective: The objective of the present study is to detect heavy metals (arsenic, lead, cadmium, mercury) and other elements within the permissible limits as per WHO guidelines present in the Siddha herbo-mineral Formulation “Venkara Mathirai”. Materials and Methods: The ingredients were collected and purified and the drug was prepared as per Siddha literature “Siddha Vaithiya Thirattu”. Here, the drug was subjected to standardization by simultaneous ICP-OES analysis equipment (PERKIN ELMER OPTIMA 5300 DV). Result: This paper revealed the therapeutic safer level of heavy metals and other elements present in Venkara Mathirai, as per WHO guidelines with the help of simultaneous ICP- OES analysis equipment (PERKIN ELMER OPTIMA 5300 DV). Conclusion: From the ICP-OES analysis reveals that Venkara Mathirai are free from heavy metals there by proving the safety of its utilization in siddha system. This study forms the base for the pharmaceutical analysis of Venkara Mathirai (VM) which will be followed by safe and efficacy studies later. Keywords: Venkara Mathirai, Siddha medicine, ICP-OES, Ulcer.