Advanced Convolutional Neural Networks for Precise White Blood Cell Subtype Classification in Medical Diagnostics

Athanasios Kanavos, Orestis Papadimitriou, Khalil Al-Hussaeni, Manolis Maragoudakis, Ioannis Karamitsos
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Abstract

White blood cell (WBC) classification is pivotal in medical image analysis, playing a critical role in the precise diagnosis and monitoring of diseases. This paper presents a novel convolutional neural network (CNN) architecture designed specifically for the classification of WBC images. Our model, trained on an extensive dataset, automates the extraction of discriminative features essential for accurate subtype identification. We conducted comprehensive experiments on a publicly available image dataset to validate the efficacy of our methodology. Comparative analysis with state-of-the-art methods shows that our approach significantly outperforms existing models in accurately categorizing WBCs into their respective subtypes. An in-depth analysis of the features learned by the CNN reveals key insights into the morphological traits—such as shape, size, and texture—that contribute to its classification accuracy. Importantly, the model demonstrates robust generalization capabilities, suggesting its high potential for real-world clinical implementation. Our findings indicate that the proposed CNN architecture can substantially enhance the precision and efficiency of WBC subtype identification, offering significant improvements in medical diagnostics and patient care.
用于医学诊断中白细胞亚型精确分类的高级卷积神经网络
白细胞(WBC)分类在医学图像分析中举足轻重,对疾病的精确诊断和监测起着关键作用。本文介绍了一种专为白细胞图像分类设计的新型卷积神经网络(CNN)架构。我们的模型在一个广泛的数据集上进行了训练,能自动提取对准确亚型识别至关重要的判别特征。我们在一个公开的图像数据集上进行了全面的实验,以验证我们方法的有效性。与最先进方法的对比分析表明,我们的方法在将白细胞准确归类为各自亚型方面明显优于现有模型。对 CNN 所学特征的深入分析揭示了形态特征(如形状、大小和纹理)的关键见解,这些特征有助于提高分类的准确性。重要的是,该模型具有强大的泛化能力,这表明它在实际临床应用中具有很大的潜力。我们的研究结果表明,所提出的 CNN 架构可以大大提高白细胞亚型识别的精度和效率,从而显著改善医疗诊断和患者护理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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