Multiple Drug Resistance in Burn Patients

Abeer Mansour Abdel Rasool, Ahmed Shoaib Karmoosh
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Abstract

Infections, the most frequent outcomes and the leading cause of death in burn patients, reproduce in milieux generated by burn lesions, Severely burned patient’s immunity is weakened, thus systemic infections such as pneumonia and urinary tract infections are likely to develop. New diseases which have come up and are hardly combatted by many drugs offer a major threat in therapy; new antimicrobial medicines and effective measures that prevent infection have to be used. Due to their high mortality, these infections form a major concern to the increasing cases of MDROs in burn victims. Given that the surfaces of burn related injuries are broad, the patients’ immune systems are compromised, while they require several surgeries and lengthy hospitalization, they are easy targets for MDROs. Among the published studies, it is revealed that multidrug-resistant organisms (MDROs) are on the rise among burn patients, which poses a threat to patient outcomes as well as the treatment of the condition. As a result of skin degeneration, long-term hospitalizations, and the necessity for invasive procedures, all of which contribute to the development of infections, burn patients are particularly vulnerable.
烧伤患者的多重耐药性
感染是烧伤病人最常见的后果和最主要的死亡原因,在烧伤病灶产生的环境中繁殖,严重烧伤病人的免疫力下降,因此很可能发生全身感染,如肺炎和尿路感染。新出现的、许多药物难以对付的疾病给治疗带来了重大威胁;必须使用新的抗菌药物和有效的预防感染措施。由于死亡率高,这些感染成为烧伤患者中 MDROs 感染病例不断增加的主要原因。由于与烧伤有关的损伤表面广泛,患者的免疫系统受损,同时需要多次手术和长时间住院,因此很容易成为 MDROs 的目标。已发表的研究显示,耐多药微生物(MDROs)在烧伤患者中呈上升趋势,这对患者的预后和病情的治疗都构成了威胁。由于皮肤退化、长期住院以及必须进行侵入性手术,所有这些都会导致感染的发生,因此烧伤患者尤其容易受到感染。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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