Innovative Approaches in Psoriasis Management: Integration of Novel Drug Delivery Systems, Herbal Medicine, and Lifestyle Modifications

Abstract

Psoriasis, a complex inflammatory skin disorder, is characterized by rapid skin cell proliferation resulting in thick, red patches covered with silvery scales. This review explores the multidimensional approach to managing psoriasis, which encompasses current therapies such as systemic medications, topical treatments, and phototherapy, all known to have potential side effects. Recognizing the associated increased risk of comorbidities like psoriatic arthritis, anxiety, and cardiovascular diseases among others, this paper also delves into the promising role of herbal medicines which are gaining popularity due to their accessibility, cost-effectiveness, and potential efficacy. Additionally, it highlights the emerging advancements in novel drug delivery systems including liposomes, nanostructured lipid carriers, and microneedles, aimed at enhancing treatment efficacy through improved drug targeting and reduced side effects. This comprehensive review seeks to provide valuable insights for the development of safer and more effective therapeutic strategies, offering a beacon of hope for those afflicted by this chronic condition and guiding future research in the field. Keywords: Psoriasis, novel drug delivery systems, liposomes, nanostructured lipid carriers, microneedles, herbal medicine, lifestyle modifications, biologic agents