Metamorphopsia with SMART syndrome: A case report.

IF 0.6 Q4 CLINICAL NEUROLOGY

Case Reports in Neurology Pub Date : 2024-07-24 DOI:10.1159/000540417

Luke Flain, Aisha Lay, Eden Gadil, Karlie James, S. Thanancheyan, Stephen Bacchi, Rudy Goh

引用次数: 0

Abstract

Introduction: SMART syndrome is a rare complication of brain radiotherapy. This is the first described presentation of SMART syndrome with metamorphopsia which responded to Aspirin, Verapamil and high dose L-Arginine therapy. Case presentation: A 43 year old man presented with three weeks of migraine headaches with metamorphopsia and complex visual hallucinations affecting the left lower quadrant of both visual fields. This occurred on a background of high dose radiotherapy for right cerebellar astrocytoma 32 years ago. MRI brain demonstrated unilateral gyriform enhancement and FLAIR hyperintense cortical swelling in the right occipital lobe consistent with SMART syndrome. Conclusion: Unusual presentations of SMART syndrome exist and require consideration in all patients with focal neurological deficit post-brain radiotherapy. Validated diagnostic and treatment modalities for SMART syndrome are urgently required.

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伴有 SMART 综合征的变性人：病例报告

简介SMART 综合征是脑部放疗的一种罕见并发症。本病例首次描述了 SMART 综合征并伴有变形性视力障碍，对阿司匹林、维拉帕米和大剂量 L-精氨酸治疗有反应。病例介绍：一名 43 岁的男子因偏头痛伴变形和复杂视幻觉影响左下象限的两个视野而就诊三周。这是在 32 年前因右侧小脑星形细胞瘤接受大剂量放疗的背景下发生的。脑部核磁共振成像显示右枕叶单侧回状增强和FLAIR高强度皮质肿胀，与SMART综合征一致。结论：SMART 综合征存在不寻常的表现形式，所有脑放疗后出现局灶性神经功能缺损的患者都需要考虑。目前迫切需要对 SMART 综合征进行有效的诊断和治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Case Reports in Neurology Medicine-Neurology (clinical)

CiteScore

1.50

自引率

0.00%

发文量

审稿时长

14 weeks

期刊介绍： This new peer-reviewed online-only journal publishes original case reports covering the entire spectrum of neurology. Clinicians and researchers are given a tool to disseminate their personal experience to a wider public as well as to review interesting cases encountered by colleagues all over the world. To complement the contributions supplementary material is welcomed. The reports are searchable according to the key words supplied by the authors; it will thus be possible to search across the entire growing collection of case reports with universally used terms, further facilitating the retrieval of specific information. Following the open access principle, the entire contents can be retrieved at no charge, guaranteeing easy access to this valuable source of anecdotal information at all times.