Comparative Study of Sublingual Misoprostol and Dinoprostone Gel in Labour Induction and Its Implication on Maternal and Neonatal Outcome

Abstract

Effective and safe induction of labour is crucial in modern obstetric practice. This study aims to compare the efficacy and safety of sublingual misoprostol versus dinoprostone gel in inducing labour. A prospective, randomized controlled trial was conducted at a tertiary care hospital. A total of 828 pregnant women requiring labour induction were randomly assigned to receive either sublingual misoprostol (n=414) or dinoprostone gel (n=414). The primary outcome was the success rate of labour induction, defined as vaginal delivery within 24 hours. Secondary outcomes included the time interval from induction to delivery, incidence of hyperstimulation syndrome, mode of delivery, and maternal and neonatal outcomes. Data were analyzed using SPSS, with statistical significance set at p