REVIEW ON NABUMETONE DERIVATIVES SYNTHESIS IN THE LAST 10 YEARS

Abstract

The focus today is on the synthesis of derivatives from the approved drugs, so decrease the chance of synthesizing a potentially toxic compound. One of the commonly used drugs is the non-steroidal anti-inflammatory drugs for the treatment of painful arthritis. Nabumetone is a non-steroidal anti-inflammatory drug. In recent years many of derivatives having different biological activities have been synthesized from nabumetone. The purpose of this review is giving sight to these derivatives in the last 10 years and the biological activities of them. KEY WORDS: nabumetone , non-steroidal anti-inflammatory, anti-inflammatory , anti-cancer, anti-bacterial.