REVIEW ON NABUMETONE DERIVATIVES SYNTHESIS IN THE LAST 10 YEARS

Hussien Ali Karim, Luma Amer Musa
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Abstract

The focus today is on the synthesis of derivatives from the approved drugs, so decrease the chance of synthesizing a potentially toxic compound. One of the commonly used drugs is the non-steroidal anti-inflammatory drugs for the treatment of painful arthritis. Nabumetone is a non-steroidal anti-inflammatory drug. In recent years many of derivatives having different biological activities have been synthesized from nabumetone. The purpose of this review is giving sight to these derivatives in the last 10 years and the biological activities of them. KEY WORDS: nabumetone , non-steroidal anti-inflammatory, anti-inflammatory , anti-cancer, anti-bacterial.
过去十年萘丁美酮衍生物合成综述
目前的重点是合成已批准药物的衍生物,以减少合成潜在毒性化合物的机会。常用药物之一是治疗关节炎疼痛的非甾体抗炎药。萘丁美酮就是一种非甾体抗炎药。近年来,从萘丁美酮中合成了许多具有不同生物活性的衍生物。关键词:萘丁美酮、非甾体抗炎药、消炎药、抗癌药、抗菌药。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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