Typical course of hippocampal sclerosis. Literature review

Abstract

The article reviews the problem of hippocampal sclerosis as the main cause of pharmacoresistant temporal lobe epilepsy. Clinical manifestations, diagnostic criteria, recommended methods of examination and treatment of hippocampal sclerosis are given. The effectiveness of surgical and medical treatments was analyzed. The relevance of this article is due to a general increase in the detection of this disease, primarily owing the improvement of neuroimaging methods. Given that this disease is relatively rare, and that surgical treatment is often delayed for many years, a review of this topic is useful for early diagnosis and improved treatment outcomes. Modern literary sources on hippocampal sclerosis were studied. The studied material is summarized and presented in the form of a literature review in this article. A search for literary sources was carried out in two main scientific databases: Scopus and PubMed. The review included original articles, research, and official guidelines from medical associations.