Additional comments on extracellular vesicles derived from mesenchymal stem cells mediate extracellular matrix remodeling in osteoarthritis

IF 3.6 3区医学 Q3 CELL & TISSUE ENGINEERING

World journal of stem cells Pub Date : 2024-07-26 DOI:10.4252/wjsc.v16.i7.739

Hang Pei, Yi Zhang, Chao Wang, Bang-Jian He

引用次数: 0

Abstract

Recently, we read an article published by the Yang et al . The results of this study indicated that engineered exosomes loaded with microRNA-29a (miR-29a) alleviate knee inflammation and maintain extracellular matrix stability in Sprague Dawley rats. The study’s results provide useful information for treating knee osteoarthritis (KOA). This letter, shares our perspectives on treating KOA using engineered exosomes for miR-29a.

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关于间充质干细胞衍生的细胞外泡介导骨关节炎细胞外基质重塑的补充评论

最近，我们读到了 Yang 等人发表的一篇文章。该研究结果表明，装载了 microRNA-29a (miR-29a) 的工程外泌体能缓解 Sprague Dawley 大鼠的膝关节炎症并维持细胞外基质的稳定性。研究结果为治疗膝骨关节炎（KOA）提供了有用的信息。这封信分享了我们对使用miR-29a工程外泌体治疗KOA的看法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

World journal of stem cells Biochemistry, Genetics and Molecular Biology-Molecular Biology

CiteScore

7.80

自引率

4.90%

发文量

750

期刊介绍： The World Journal of Stem Cells (WJSC) is a leading academic journal devoted to reporting the latest, cutting-edge research progress and findings of basic research and clinical practice in the field of stem cells. It was launched on December 31, 2009 and is published monthly (12 issues annually) by BPG, the world''s leading professional clinical medical journal publishing company.