Mexican Registry of Cardiomyopathies: baseline data, diagnostic strategies, and treatment approaches in Mexico.

Guillermo A Llamas-Esperón, Enrique A Berrios-Bárcenas, Jorge E Cossío-Aranda, Sylvia Salmun-Nehmad, Rahab A Morales Flores, Maria C Escalante-Seyffert, Jorge Leal-Cavazos, Eufracino Sandoval-Rodríguez, Eduardo Pamplona-Ávila, Enrique Sánchez-Hiza, Liliana E Ramos-Villalobos, Luisa F Aguilera-Mora, Mario A Benavides-González, Carlos D Carrillo, Guillermo Llamas-Delgado, Jonathan H Zaldívar-Zurita, Norberto Matadamas-Hernández
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Abstract

Objectives: The study aimed to know the clinical, demographic, diagnostic, and treatments characteristics in patients with cardiomyopathies in Mexico.

Methods: The Mexican Registry of Cardiomyopathies (REMEMI) is an observational, prospective and national study of patients with cardiomyopathies, which includes: Dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM), restrictive cardiomyopathy (RCM) and arrhythmogenic cardiomyopathy of the right ventricle (ARVC).

Results: A total of 1026 patients from most states of the Mexican Republic (19) were included, with 494 corresponding to DCM, 490 to HCM, 35 to RCM, and seven to ARVC. We found significant differences between the various cardiomyopathy phenotypes (p < 0.05) in the coexistence with diabetes, use of implantable defibrillator, presence of ventricular tachycardia, and NYHA functional class ≥ 1. There were no significant differences in age and predominant gender between each one. When analyzing by phenotype, we found that patients with HCM have limited use of diagnostic methods considered indispensable, such as cardiac magnetic resonance, Holter monitoring, and genetic testing in patients and their relatives.

Conclusion: Seeking contemporary information through observational registries in Mexico is a valuable opportunity to understand the characteristics of the methods used in the study and treatment of diseases such as cardiomyopathies by Mexican physicians. It can provide information for the implementation of management guidelines and strategies to disseminate findings to improve healthcare in our country.

墨西哥心肌病登记处:墨西哥的基线数据、诊断策略和治疗方法。
研究目的研究旨在了解墨西哥心肌病患者的临床、人口统计学、诊断和治疗特点:墨西哥心肌病登记处(REMEMI)是一项针对心肌病患者的全国性前瞻性观察研究,其中包括结果:来自墨西哥大部分地区的 1026 名心肌病患者接受了该研究,其中包括:扩张型心肌病 (DCM)、肥厚型心肌病 (HCM)、限制型心肌病 (RCM) 和右心室致心律失常性心肌病 (ARVC):共纳入了来自墨西哥共和国大部分州(19 个州)的 1026 名患者,其中 494 人患有 DCM,490 人患有 HCM,35 人患有 RCM,7 人患有 ARVC。我们发现,各种心肌病表型在合并糖尿病、使用植入式除颤器、室性心动过速和 NYHA 功能分级≥ 1 等方面存在明显差异(p < 0.05)。不同患者的年龄和主要性别无明显差异。通过表型分析,我们发现 HCM 患者对心脏磁共振、Holter 监测、患者及其亲属基因检测等不可或缺的诊断方法的使用有限:通过墨西哥的观察性登记寻求当代信息,是了解墨西哥医生在研究和治疗心肌病等疾病时所用方法特点的宝贵机会。它可以为实施管理指南和传播研究结果的战略提供信息,从而改善我国的医疗保健。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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