Liver Transplantation: A Test of Cellular Physiology, Preservation, and Injury.

IF 5.3 2区医学 Q1 PHYSIOLOGY

Physiology Pub Date : 2024-11-01 Epub Date: 2024-07-30 DOI:10.1152/physiol.00020.2024

B Martins, J Mossemann, F Aguilar, S Zhao, P J Bilan, B A Sayed

引用次数: 0

Abstract

Liver transplantation has evolved into a mature clinical field, but scarcity of usable organs poses a unique challenge. Expanding the donor pool requires novel approaches for protecting hepatic physiology and cellular homeostasis. Here we define hepatocellular injury during transplantation, with an emphasis on modifiable cell death pathways as future therapeutics.

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肝脏移植：细胞生理、保存和损伤的考验。

肝移植已发展成为一个成熟的临床领域，但可用器官的稀缺性带来了独特的挑战。扩大供体库需要采用新的方法来保护肝脏生理和细胞稳态。在这里，我们定义了移植过程中的肝细胞损伤，重点是作为未来疗法的可改变的细胞死亡途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Physiology 医学-生理学

CiteScore

14.50

自引率

0.00%

发文量

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