Femoroacetabular impingement syndrome in middle-aged individuals is strongly associated with the development of hip osteoarthritis within 10-year follow-up: a prospective cohort study (CHECK).

IF 11.6 1区 医学 Q1 SPORT SCIENCES
Rintje Agricola, Michiel M A van Buuren, Joanne L Kemp, Harrie Weinans, Jos Runhaar, Sita M A Bierma-Zeinstra
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引用次数: 0

Abstract

Objective: The objective is to determine the association and absolute risk of femoroacetabular impingement syndrome (FAIS) for the development of radiographic hip osteoarthritis (RHOA).

Methods: This is a nationwide, multicentre prospective cohort study (Cohort Hip and Cohort Knee) with 1002 individuals aged between 45 and 65 years. Hips without definitive RHOA (Kellgren-Lawrence (KL) grade≤1) at baseline and with anteroposterior pelvic radiographs at baseline and 10-year follow-up available (n=1386 hips) were included. FAIS was defined by the baseline presence of a painful hip, limited internal hip rotation≤25° and cam morphology defined by an alpha angle>60°. The outcomes were incident RHOA (KL grade≥2 or total hip replacement (THR)) and incident end-stage RHOA (KL≥3 or THR) within 10 years.

Results: Of the 1386 included hips (80% women; mean age 55.7±5.2 years), 21 hips fulfilled criteria for FAIS and 563 hips did not fulfil any of the FAIS criteria (reference group; no symptoms, no signs, no cam morphology). Within 10-year follow-up, 221 hips (38%) developed incident RHOA and 15 hips (3%) developed end-stage RHOA (including 9 hips with THR). Adjusted for sex, age and body mass index, FAIS with cam morphology resulted in an OR of 6.85 (95% CI 2.10 to 22.35) for incident RHOA and 47.82 (95% CI 12.51 to 182.76) for incident end-stage RHOA, compared with hips not having any FAIS criteria. The absolute risk of FAIS was 81% for incident RHOA and 33% for incident end-stage RHOA.

Conclusion: FAIS was strongly associated with the development of RHOA within 10 years. Although the baseline prevalence of FAIS was low, the high absolute risk of FAIS for RHOA warrants further studies to determine preventive strategies.

中年人股骨髋臼撞击综合征与 10 年随访期内髋关节骨性关节炎的发展密切相关:一项前瞻性队列研究 (CHECK)。
目的目的是确定股骨髋臼撞击综合征(FAIS)与放射性髋关节骨性关节炎(RHOA)发病的相关性和绝对风险:这是一项全国范围的多中心前瞻性队列研究(队列髋关节和队列膝关节),共有 1002 名年龄在 45 岁至 65 岁之间的患者参加。研究对象包括基线无明确RHOA(Kellgren-Lawrence(KL)分级≤1)的髋关节,以及基线和10年随访时有骨盆正侧位X光片的髋关节(1386个)。FAIS的定义是基线存在髋关节疼痛、髋关节内旋受限≤25°以及凸轮形态定义为α角>60°。结果为10年内发生的RHOA(KL≥2级或全髋关节置换术(THR))和终末期RHOA(KL≥3级或THR):在纳入的 1386 个髋关节(80% 为女性;平均年龄为 55.7±5.2 岁)中,21 个髋关节符合 FAIS 标准,563 个髋关节不符合任何 FAIS 标准(参照组;无症状、无体征、无凸轮形态)。在10年的随访中,有221个髋关节(38%)发生了RHOA,15个髋关节(3%)发生了终末期RHOA(包括9个髋关节进行了全髋关节置换术)。经性别、年龄和体重指数调整后,与不具备任何FAIS标准的髋关节相比,具有凸轮形态的FAIS导致发生RHOA的OR值为6.85(95% CI为2.10至22.35),导致发生终末期RHOA的OR值为47.82(95% CI为12.51至182.76)。发生FAIS的绝对风险在RHOA中为81%,在终末期RHOA中为33%:结论:FAIS与10年内发生RHOA密切相关。虽然FAIS的基线发病率较低,但FAIS导致RHOA的绝对风险较高,因此有必要进一步研究以确定预防策略。
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来源期刊
CiteScore
27.10
自引率
4.90%
发文量
217
审稿时长
3-8 weeks
期刊介绍: The British Journal of Sports Medicine (BJSM) is a dynamic platform that presents groundbreaking research, thought-provoking reviews, and meaningful discussions on sport and exercise medicine. Our focus encompasses various clinically-relevant aspects such as physiotherapy, physical therapy, and rehabilitation. With an aim to foster innovation, education, and knowledge translation, we strive to bridge the gap between research and practical implementation in the field. Our multi-media approach, including web, print, video, and audio resources, along with our active presence on social media, connects a global community of healthcare professionals dedicated to treating active individuals.
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