Paediatric postoperative acute kidney injury after non-cardiac surgery: Protocol for a systematic review and meta-analysis.

IF 1.9 4区医学 Q2 ANESTHESIOLOGY

Acta Anaesthesiologica Scandinavica Pub Date : 2024-11-01 Epub Date: 2024-07-30 DOI:10.1111/aas.14505

Arash Emami, Ebba Sivertsson, Johan Westerbergh, Michael Hultström, Johan Danielsson, Peter Frykholm, Robert Frithiof

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引用次数: 0

Abstract

Background: Paediatric acute kidney injury (AKI) is associated with significant adverse outcomes such as increased mortality, progression to chronic kidney disease and longer length of stay in hospital. Postoperative AKI is a common and recognized complication after surgery in adults. In the paediatric population, AKI postoperatively to cardiac surgery has been extensively studied. However, the incidence of postoperative AKI after non-cardiac surgery is less clear. Therefore, we aim to assess the available literature on this topic.

Methods: We will conduct a systematic review of observational and randomized controlled trials assessing the incidence of paediatric postoperative AKI after non-cardiac surgery. Pairs of reviewers will independently screen the literature and extract data and assess risk of bias from eligible studies. The databases Pubmed, Cochrane and Web of Sciences will be searched. We will conduct the review in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines and the Grading of Recommendation, Assessment, Development and Evaluation (GRADE) approach. If sufficient homogeneity within the included trials we will conduct meta-analyses.

Discussion: This systematic review aims to investigate the incidence of postoperative AKI in the paediatric non-cardiac surgery population. The results of this review will provide a foundation for future research in the field of paediatric postoperative AKI.

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非心脏手术后儿科术后急性肾损伤：系统综述和荟萃分析协议。

背景：小儿急性肾损伤（AKI）与严重的不良后果相关，如死亡率增加、慢性肾病恶化和住院时间延长。术后 AKI 是成人手术后常见且公认的并发症。在儿科人群中，心脏手术术后 AKI 已被广泛研究。然而，非心脏手术术后 AKI 的发生率却不太清楚。因此，我们旨在评估有关这一主题的现有文献：我们将对评估非心脏手术后儿科术后 AKI 发生率的观察性和随机对照试验进行系统性回顾。两对审稿人将独立筛选文献，从符合条件的研究中提取数据并评估偏倚风险。我们将检索 Pubmed、Cochrane 和 Web of Sciences 等数据库。我们将根据《系统性综述和荟萃分析首选报告项目》（PRISMA）指南和《推荐、评估、发展和评价分级》（GRADE）方法进行综述。如果纳入的试验具有足够的同质性，我们将进行荟萃分析：本系统综述旨在研究儿科非心脏手术人群术后 AKI 的发生率。本综述的结果将为儿科术后 AKI 领域的未来研究奠定基础。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta Anaesthesiologica Scandinavica 医学-麻醉学

CiteScore

4.30

自引率

9.50%

发文量

157

审稿时长

3-8 weeks

期刊介绍： Acta Anaesthesiologica Scandinavica publishes papers on original work in the fields of anaesthesiology, intensive care, pain, emergency medicine, and subjects related to their basic sciences, on condition that they are contributed exclusively to this Journal. Case reports and short communications may be considered for publication if of particular interest; also letters to the Editor, especially if related to already published material. The editorial board is free to discuss the publication of reviews on current topics, the choice of which, however, is the prerogative of the board. Every effort will be made by the Editors and selected experts to expedite a critical review of manuscripts in order to ensure rapid publication of papers of a high scientific standard.