Simian retrovirus transmission in rhesus macaques

IF 0.8 4区农林科学 Q3 VETERINARY SCIENCES

Journal of Medical Primatology Pub Date : 2024-07-28 DOI:10.1111/jmp.12726

Peter Nham, Bryson Halley, Koen K. A. Van Rompay, Jeffrey Roberts, JoAnn Yee

引用次数: 0

Abstract

Historically, to generate Simian Retrovirus (SRV) positive control materials, we performed in vivo passage by inoculating uninfected rhesus macaques with whole blood from an SRV-1 infected (antibody and PCR positive) macaque. However, recent attempts using this approach have failed. This study reports observations and explores why it has become more difficult to transmit SRV via in vivo passage.

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猕猴体内的猿逆转录病毒传播。

一直以来，为了生成猿逆转录病毒（SRV）阳性对照材料，我们都是通过给未感染的猕猴接种 SRV-1 感染（抗体和 PCR 阳性）猕猴的全血来进行体内传代。然而，最近使用这种方法的尝试都失败了。本研究报告了观察结果，并探讨了为什么通过体内穿刺传播 SRV 变得越来越困难。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Medical Primatology 生物-动物学

CiteScore

1.40

自引率

42.90%

发文量

审稿时长

6 months

期刊介绍： The Journal of Medical Primatology publishes research on non-human primates as models to study, prevent, and/or treat human diseases; subjects include veterinary medicine; morphology, physiology, reproductive biology, central nervous system, and cardiovascular diseases; husbandry, handling, experimental methodology, and management of non-human primate colonies and laboratories; non-human primate wildlife management; and behaviour and sociology as related to medical conditions and captive non-human primate needs. Published material includes: Original Manuscripts - research results; Case Reports - scientific documentation of a single clinical study; Short Papers - case histories, methodologies, and techniques of particular interest; Letters to the Editor - opinions, controversies and sporadic scientific observations; Perspectives – opinion piece about existing research on a particular topic; Minireviews – a concise review of existing literature; Book Reviews by invitation; Special Issues containing selected papers from specialized meetings; and Editorials and memoriams authored by the Editor-in-Chief.