ThunderBolt: An interactive data sharing and analysis platform for large-omics experiments

Abstract

Summary: Mass-spectrometry (MS) datasets present a unique set of challenges that make in-depth bioinformatics analysis non-trivial, with analysis requiring both expertise and time. Often these datasets have unique structures that need to be dealt with on an individual basis. Currently, tools providing a fast, interactive and guided way of exploring and analysing these data sets are not readily available. To this end, we have developed ThunderBolt: a highly interactive, point-and-click web-based application providing both bioinformaticians and biologists with a platform for i) searching and comparing multiple omics datasets, ii) fast data exploration and quality control, iii) interactive visualization, iv) pre-processing, v) statistical analysis and vi) functional and network enrichment analysis of large proteomics datasets using the Shiny framework. Availability: ThunderBolt is a shiny-application accessible at https://thunderbolt.sydney.edu.au/