Recent Development of a Traditional Herbal Medicine, Stixis suaveolens (Roxb.) Pierre: Its Botany, Ethnomedicine, Phytochemistry, Pharmacology, and Toxicology

IF 1.5 4区 医学 Q4 CHEMISTRY, MEDICINAL
Tran Van Chen, Nguyen Trong Nghia, Nguyen Thi Thu Hien
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Abstract

Background/ObjectivePlant-based products and their isolated compounds have been utilized in traditional medicine since early times. In folk medicine, Stixis suaveolens (Roxb.) Pierre has been used to treat painful tendons and bones, rheumatism, eye infections, cough, malaria, asthma, and cardiovascular diseases. This study aims to summarize up-to-date botany, ethnomedicine, phytochemical components, pharmacological effects, and toxicology.MethodsInformation on S. suaveolens was collected from databases such as the Web of Science, Scopus, Google Scholar, PubMed, Science Direct, Springer, and others.ResultsS. suaveolens has been demonstrated to possess various pharmacological effects, including antioxidant, antimicrobial, anti-inflammatory, antidiabetic, antidepressant, antidiarrheal, hepatoprotective, analgesic, antihemolytic, and thrombolytic activities. Phytochemical studies of this species have revealed the presence of secondary metabolites, including lignans, phenolics, alkaloids, and volatile components.ConclusionThe pharmacological effects of the extracts and bioactive compounds resulting from the experimental studies in the review support the traditional uses of S. suaveolens. They could be useful in developing novel pharmacological applications in the treatment of various acute and chronic human ailments. The efficacy, safety, and toxicity of S. suaveolens plant in enhancing therapeutic efficacy should be investigated widely in further studies.
传统草药 Stixis suaveolens (Roxb.) Pierre 的最新发展:植物学、民族医药学、植物化学、药理学和毒理学
背景/目的植物类产品及其分离化合物很早就被用于传统医药中。在民间医药中,皮埃尔(Stixis suaveolens (Roxb.) Pierre)被用于治疗筋骨疼痛、风湿、眼部感染、咳嗽、疟疾、哮喘和心血管疾病。本研究旨在总结最新的植物学、民族医药学、植物化学成分、药理作用和毒理学。方法从 Web of Science、Scopus、Google Scholar、PubMed、Science Direct、Springer 等数据库中收集有关 S. suaveolens 的信息。结果已证明蛇床子具有多种药理作用,包括抗氧化、抗菌、抗炎、抗糖尿病、抗抑郁、止泻、保肝、镇痛、抗溶血和溶栓活性。对该物种进行的植物化学研究表明,其存在次生代谢物,包括木脂素、酚类、生物碱和挥发性成分。它们可用于开发治疗人类各种急慢性疾病的新型药理应用。应在进一步的研究中广泛调查 S. suaveolens 植物在提高疗效方面的功效、安全性和毒性。
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来源期刊
Natural Product Communications
Natural Product Communications 工程技术-食品科技
CiteScore
3.10
自引率
11.10%
发文量
254
审稿时长
2.7 months
期刊介绍: Natural Product Communications is a peer reviewed, open access journal studying all aspects of natural products, including isolation, characterization, spectroscopic properties, biological activities, synthesis, structure-activity, biotransformation, biosynthesis, tissue culture and fermentation. It covers the full breadth of chemistry, biochemistry, biotechnology, pharmacology, and chemical ecology of natural products. Natural Product Communications is a peer reviewed, open access journal studying all aspects of natural products, including isolation, characterization, spectroscopic properties, biological activities, synthesis, structure-activity, biotransformation, biosynthesis, tissue culture and fermentation. It covers the full breadth of chemistry, biochemistry, biotechnology, pharmacology, and chemical ecology of natural products. Natural Product Communications is a peer reviewed, open access journal studying all aspects of natural products, including isolation, characterization, spectroscopic properties, biological activities, synthesis, structure-activity, biotransformation, biosynthesis, tissue culture and fermentation. It covers the full breadth of chemistry, biochemistry, biotechnology, pharmacology, and chemical ecology of natural products.
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