{"title":"Mechanics and mechanobiology of intracranial aneurysms","authors":"JD Humphrey","doi":"10.1177/10812865231219163","DOIUrl":null,"url":null,"abstract":"Rupture of intracranial aneurysms, either fusiform or saccular in shape, associates with significant morbidity and mortality. The progressive enlargement and eventual rupture of these lesions depends strongly on the associated mechanics and mechanobiology. In this paper, we review results from past biomechanical analyses of intracranial aneurysms and highlight lessons learned in the general area of vascular mechanobiology with the goal of guiding future research.","PeriodicalId":49854,"journal":{"name":"Mathematics and Mechanics of Solids","volume":"160 1","pages":""},"PeriodicalIF":1.7000,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Mathematics and Mechanics of Solids","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1177/10812865231219163","RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Rupture of intracranial aneurysms, either fusiform or saccular in shape, associates with significant morbidity and mortality. The progressive enlargement and eventual rupture of these lesions depends strongly on the associated mechanics and mechanobiology. In this paper, we review results from past biomechanical analyses of intracranial aneurysms and highlight lessons learned in the general area of vascular mechanobiology with the goal of guiding future research.
期刊介绍:
Mathematics and Mechanics of Solids is an international peer-reviewed journal that publishes the highest quality original innovative research in solid mechanics and materials science.
The central aim of MMS is to publish original, well-written and self-contained research that elucidates the mechanical behaviour of solids with particular emphasis on mathematical principles. This journal is a member of the Committee on Publication Ethics (COPE).