{"title":"Five anti-inflammatory compounds from the resins of Liquidambar orientalis","authors":"Hao Chen , Sheng-Hong Li , Yong-Xian Cheng","doi":"10.1080/10286020.2024.2379978","DOIUrl":null,"url":null,"abstract":"<div><div>Five undescribed compounds, including a triterpenoid (<strong>1</strong>), three phenylpropanoids [(±)−<strong>2</strong> and <strong>4</strong>], and an aromatic compound (<strong>3</strong>), as well as six known analogues (<strong>5</strong>–<strong>10</strong>), were isolated from the resins of <em>Liquidambar orientalis</em> Mill. Their structures, including absolute configurations, were determined by using spectroscopic and computational methods, and the five new compounds displayed anti-inflammatory activities in LPS-induced RAW264.7 cells.</div></div>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":"27 1","pages":"Pages 1-10"},"PeriodicalIF":1.3000,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Asian Natural Products Research","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S1028602024001231","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
引用次数: 0
Abstract
Five undescribed compounds, including a triterpenoid (1), three phenylpropanoids [(±)−2 and 4], and an aromatic compound (3), as well as six known analogues (5–10), were isolated from the resins of Liquidambar orientalis Mill. Their structures, including absolute configurations, were determined by using spectroscopic and computational methods, and the five new compounds displayed anti-inflammatory activities in LPS-induced RAW264.7 cells.
期刊介绍:
The Journal of Asian Natural Products Research (JANPR) publishes chemical and pharmaceutical studies in the English language in the field of natural product research on Asian ethnic medicine. The journal publishes work from scientists in Asian countries, e.g. China, Japan, Korea and India, including contributions from other countries concerning natural products of Asia. The journal is chemistry-orientated. Major fields covered are: isolation and structural elucidation of natural constituents (including those for non-medical uses), synthesis and transformation (including biosynthesis and biotransformation) of natural products, pharmacognosy, and allied topics. Biological evaluation of crude extracts are acceptable only as supporting data for pure isolates with well-characterized structures.
All published research articles in this journal have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by at least two expert referees.