Individual and joint associations of air pollutants exposure with semen quality: A retrospective longitudinal study in Wenzhou, China.

IF 2.6 3区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

International Archives of Occupational and Environmental Health Pub Date : 2024-10-01 Epub Date: 2024-07-26 DOI:10.1007/s00420-024-02095-7

Xuchao Dai, Guangyuan Liu, Chengshuang Pan, Feidi Li, Yawen Liu, Jiaxin Liu, Gang Chen, Mengqi Zhang, Qianjin Fei, Jiujia Zheng, Hong Huang, Zhigang Wu

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引用次数: 0

Abstract

Purpose: The impact of air pollution on semen quality has been confirmed, yet the joint effect remains unclear. We evaluate the individual and joint associations of particulate (PM_2.5 and PM₁₀) and gaseous pollutants (NO₂, SO₂, O₃ and CO) with semen quality.

Methods: We included 5,114 men in this study from 2014 to 2022. The individual and joint associations were measured by multiple linear regression models.

Results: Sperm motility and semen volume were inversely associated with pollutant concentrations during every stage of sperm development, especially at lag days 0-9 and 10-14 (all P < 0.05). Stratified analyses showed that the study pollutants (except CO) had a positive effect on semen concentration during the stage of sperm development, especially in spring and autumn, while a decreased total sperm number was associated with CO (all P < 0.05). However, joint associations of particulate and gaseous pollutants with semen quality parameters were not statistically significant (all P > 0.05).

Conclusions: During all stages of sperm development, particulate and gaseous pollutants had individual negative impacts on sperm motility and semen volume, and these impacts were less pronounced in spring and autumn. Our findings highlight the importance and necessity of reducing the exposure to pollutants especially in the critical stage of sperm development to improve semen quality.

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空气污染物暴露与精液质量的个体和联合关联：中国温州的一项回顾性纵向研究。

目的：空气污染对精液质量的影响已得到证实，但其联合影响仍不明确。我们评估了颗粒物（PM2.5 和 PM10）和气体污染物（二氧化氮、二氧化硫、臭氧和一氧化碳）对精液质量的单独和联合影响：我们在 2014 年至 2022 年期间对 5114 名男性进行了研究。结果：精子活力和精液质量与空气污染物（二氧化氮、二氧化硫、臭氧、三氧化碳和一氧化碳）的相关性通过多元线性回归模型进行了测量：结果：在精子发育的各个阶段，精子活力和精液量都与污染物浓度成反比，尤其是在精子发育的第 0-9 天和第 10-14 天（均为 P0.05）：在精子发育的各个阶段，颗粒污染物和气态污染物都会对精子活力和精液量产生负面影响，这些影响在春季和秋季不太明显。我们的研究结果凸显了减少污染物暴露的重要性和必要性，尤其是在精子发育的关键阶段，以提高精液质量。

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来源期刊

International Archives of Occupational and Environmental Health 医学-公共卫生、环境卫生与职业卫生

CiteScore

5.60

自引率

6.70%

发文量

127

审稿时长

3 months

期刊介绍： International Archives of Occupational and Environmental Health publishes Editorials, Review Articles, Original Articles, and Letters to the Editor. It welcomes any manuscripts dealing with occupational or ambient environmental problems, with a special interest in research at the interface of occupational health and clinical medicine. The scope ranges from Biological Monitoring to Dermatology, from Fibers and Dust to Human Toxicology, from Nanomaterials and Ultra-fine Dust to Night- and Shift Work, from Psycho-mental Distress and Burnout to Vibrations. A complete list of topics can be found on the right-hand side under For authors and editors. In addition, all papers should be based on present-day standards and relate to: -Clinical and epidemiological studies on morbidity and mortality -Clinical epidemiological studies on the parameters relevant to the estimation of health risks -Human experimental studies on environmental health effects. Animal experiments are only acceptable if relevant to pathogenic aspects. -Methods for studying the topics mentioned above.