Sweetening mitochondria: Hexokinase shields mitochondria from fission when glucose is low

IF 14.5 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Molecular Cell Pub Date : 2024-07-25 DOI:10.1016/j.molcel.2024.06.035

引用次数: 0

Abstract

In this issue of Molecular Cell, Pilic et al.¹ show that hexokinase, the first enzyme of glycolysis, forms perimitochondrial rings that prevent mitochondrial fragmentation when ATP levels drop.

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使线粒体变甜当葡萄糖含量低时，Hexokinase 保护线粒体不发生分裂

在本期的《分子细胞》（Molecular Cell）杂志上，Pilic 等人1 发现糖酵解的第一种酶己糖激酶会在线粒体周围形成环，当 ATP 水平下降时防止线粒体破碎。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Molecular Cell 生物-生化与分子生物学

CiteScore

26.00

自引率

3.80%

发文量

389

审稿时长

1 months

期刊介绍： Molecular Cell is a companion to Cell, the leading journal of biology and the highest-impact journal in the world. Launched in December 1997 and published monthly. Molecular Cell is dedicated to publishing cutting-edge research in molecular biology, focusing on fundamental cellular processes. The journal encompasses a wide range of topics, including DNA replication, recombination, and repair; Chromatin biology and genome organization; Transcription; RNA processing and decay; Non-coding RNA function; Translation; Protein folding, modification, and quality control; Signal transduction pathways; Cell cycle and checkpoints; Cell death; Autophagy; Metabolism.

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