The Need to Analyze Telogen Effluvium and Alopecia Areata Parallelly in Long COVID Studies

IF 4.3 4区 医学 Q1 INFECTIOUS DISEASES
Chia-Tse Weng, Kai-Che Wei, Chao-Chun Yang
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引用次数: 0

Abstract

I am writing in response to the article titled “Risks of alopecia areata in long COVID: Binational population-based cohort studies from South Korea and Japan” by Kyung et al., recently published in the Journal of Medical Virology [1]. The study provides robust evidence on the association between SARS-CoV-2 infection and the increased risk of developing alopecia areata (AA) as part of long COVID. It also highlights the significant impact of COVID-19 severity and vaccination status on AA risk.

Telogen effluvium (TE) is another type of hair loss that could be highly relevant to COVID-19 and long COVID [2]. TE and AA have overlapping clinical manifestations, but TE is not as well-known as AA by physicians. Therefore, misclassification between TE and AA is possible. TE is characterized by diffuse hair shedding often triggered by significant stress, illness, or hormonal changes [3]. Given the profound stress and physiological changes associated with COVID-19, TE is a common postinfection manifestation [4]. Furthermore, the severity of COVID-19 has been correlated with an increased risk of TE [5].

To provide a comprehensive understanding of post-COVID-19 hair loss patterns, it is advisable to present TE and AA in parallel using the existing database. This approach could yield significant insights into the prevalence of hair loss in long COVID. While the database may not confirm the accuracy of AA versus TE diagnoses, presenting results for both conditions can help clarify their respective impacts.

It is prudent to acknowledge that dermatologists have a relatively clear understanding of the differences between TE and AA. Therefore, it might be beneficial for the authors to consider limiting AA diagnoses to those confirmed by dermatologists to enhance diagnostic accuracy and reliability. Furthermore, comparing hair loss caused by other viral infections, such as influenza, which is more frequently reported to cause AA and less often reported to cause TE [6], can enhance the overall understanding of virus-associated alopecia.

In conclusion, while the study by Kyung et al. provides significant insights into the risk of AA following COVID-19, incorporating the diagnosis of TE, applying stricter criteria for diagnosing AA, and considering additional control groups in future research would offer a more holistic view of postinfection hair loss. This approach could enhance our understanding of long COVID and improve patient care strategies.

Chia-Tse Weng and Kai-Che Wei wrote the manuscript. Chao-Chun Yang substantively revised it. All authors read and approved the final manuscript.

The authors declare no conflicts of interest.

在长期 COVID 研究中同时分析脱发和白发的必要性。
Kyung 等人最近在《医学病毒学杂志》(Journal of Medical Virology)上发表了一篇题为 "Risks of alopecia areata in long COVID: Binational population-based cohort studies from South Korea and Japan "的文章[1]。该研究提供了有力的证据,证明 SARS-CoV-2 感染与长 COVID 中秃发症(AA)发病风险增加之间存在关联。脱发(TE)是与 COVID-19 和长期 COVID 高度相关的另一种脱发类型[2]。TE和AA有重叠的临床表现,但TE并不像AA那样为医生所熟知。因此,TE 和 AA 有可能被误诊。TE的特征是头发弥漫性脱落,通常由重大压力、疾病或激素变化引发[3]。鉴于 COVID-19 带来的巨大压力和生理变化,TE 是一种常见的感染后表现 [4]。此外,COVID-19 的严重程度与 TE 风险的增加有关 [5]。为了全面了解 COVID-19 后的脱发模式,最好利用现有数据库同时显示 TE 和 AA。这种方法可以对长 COVID 脱发的普遍性产生重大影响。虽然数据库可能无法确认 AA 和 TE 诊断的准确性,但展示这两种情况的结果有助于澄清它们各自的影响。因此,作者不妨考虑将 AA 诊断限制在皮肤科医生确诊的范围内,以提高诊断的准确性和可靠性。总之,虽然 Kyung 等人的研究对 COVID-19 后 AA 的风险提供了重要见解,但在未来的研究中纳入 TE 诊断、应用更严格的 AA 诊断标准以及考虑额外的对照组,将为我们提供一个更全面的感染后脱发视角。这种方法可以加深我们对长COVID的理解,并改善患者护理策略。翁嘉泽和魏凯哲撰写了手稿,杨超春对手稿进行了实质性修改。所有作者都阅读并批准了最终手稿。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
7.20
自引率
4.50%
发文量
120
审稿时长
6-12 weeks
期刊介绍: Influenza and Other Respiratory Viruses is the official journal of the International Society of Influenza and Other Respiratory Virus Diseases - an independent scientific professional society - dedicated to promoting the prevention, detection, treatment, and control of influenza and other respiratory virus diseases. Influenza and Other Respiratory Viruses is an Open Access journal. Copyright on any research article published by Influenza and Other Respiratory Viruses is retained by the author(s). Authors grant Wiley a license to publish the article and identify itself as the original publisher. Authors also grant any third party the right to use the article freely as long as its integrity is maintained and its original authors, citation details and publisher are identified.
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