Safety Assessment of Polyol Phosphates as Used in Cosmetics.

IF 1.2 4区 医学 Q4 PHARMACOLOGY & PHARMACY
International Journal of Toxicology Pub Date : 2024-10-01 Epub Date: 2024-07-24 DOI:10.1177/10915818241259699
Wilbur Johnson, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler, James G Marks, Ronald C Shank, Thomas J Slaga, Paul W Snyder, Monice Fiume, Bart Heldreth
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引用次数: 0

Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 10 polyol phosphates. Some of the possible functions in cosmetics that are reported for this ingredient group are chelating agents, oral care agents, and skin conditioning agents. The Panel reviewed relevant data relating to the safety of these ingredients under the intended conditions of use in cosmetic formulations, and concluded that Sodium Phytate, Phytic Acid, Phytin, and Trisodium Inositol Triphosphate are safe in cosmetics in the present practices of use and concentration described in the safety assessment. The Panel also concluded that the data are insufficient to determine the safety of the following 6 ingredients as used in cosmetics: Disodium Glucose Phosphate, Manganese Fructose Diphosphate, Sodium Mannose Phosphate, Trisodium Fructose Diphosphate, Xylityl Phosphate, and Zinc Fructose Diphosphate.

化妆品中使用的多元醇磷酸盐的安全评估。
化妆品成分安全专家小组(专家小组)审查了 10 种多元醇磷酸盐的安全性。据报告,这类成分在化妆品中可能具有的一些功能包括螯合剂、口腔护理剂和皮肤调理剂。专家小组审查了与这些成分在化妆品配方中预期使用条件下的安全性有关的相关数据,并得出结论认为,按照目前的使用方法和安全评估中所述的浓度,植酸钠、植酸、植素和三磷酸肌醇三钠盐在化妆品中是安全的。专家小组还得出结论,数据不足以确定以下 6 种成分在化妆品中使用的安全性:葡萄糖磷酸酯二钠、果糖二磷酸锰、甘露糖磷酸酯钠、果糖二磷酸三钠、木糖醇磷酸酯和果糖二磷酸锌。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.40
自引率
4.50%
发文量
53
审稿时长
4.5 months
期刊介绍: The International Journal of Toxicology publishes timely, peer-reviewed papers on current topics important to toxicologists. Six bi-monthly issues cover a wide range of topics, including contemporary issues in toxicology, safety assessments, novel approaches to toxicological testing, mechanisms of toxicity, biomarkers, and risk assessment. The Journal also publishes invited reviews on contemporary topics, and features articles based on symposia. In addition, supplemental issues are routinely published on various special topics, including three supplements devoted to contributions from the Cosmetic Review Expert Panel.
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