Application of botulinum toxin in the repair of a complex ventral hernia.

S D Israel Benchaya, D J Peláez Mata, M A García-Casillas, I Bada Bosch, S Monje Fuente, A M Lancharro Zapata, J C De Agustín
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Abstract

Introduction: Preoperative application of botulinum toxin type A has demonstrated to be safe and effective in the closure of complex ventral hernias in adults. However, its use in pediatrics has been little documented.

Case report: We present the case of a 22-month-old girl with a complex abdominal wall ventral hernia secondary to multiple neonatal laparotomies. In a first procedure, botulinum toxin was administered using an intramuscular approach at six sites of the muscle layers surrounding the defect, under general anesthesia and ultrasound control. 4 weeks later, an open hernia repair was conducted, without complications.

Discussion: Botulinum toxin at low doses could facilitate the surgical treatment of complex ventral incisional hernias in children. Even though it is important to adjust dosage and anatomical reference points according to hernia type and patient age and weight, further studies are required to optimize these variables.

应用肉毒杆菌毒素修复复杂腹股沟疝。
导言:事实证明,术前应用 A 型肉毒毒素对成人复杂腹股沟疝的闭合是安全有效的。然而,该疗法在儿科的应用却鲜有记载:本病例是一名 22 个月大的女孩,因新生儿多次开腹手术而继发复杂腹壁腹股沟疝。在第一次手术中,在全身麻醉和超声波控制下,通过肌肉注射的方式在缺损周围肌肉层的六个部位注射了肉毒杆菌毒素。4周后,进行了开放性疝修补术,未出现并发症:讨论:小剂量肉毒杆菌毒素可促进儿童腹侧复杂切口疝的手术治疗。尽管根据疝气类型、患者年龄和体重调整剂量和解剖参考点非常重要,但仍需进一步研究以优化这些变量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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