Optimizing neurointerventional procedures: an algorithm for embolization coil detection and automated collimation to enable dose reduction.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2024-07-01 Epub Date: 2024-07-17 DOI:10.1117/1.JMI.11.4.044003
Arpitha Ravi, Philipp Bernhardt, Mathis Hoffmann, Richard Obler, Cuong Nguyen, Andreas Berting, René Chapot, Andreas Maier
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引用次数: 0

Abstract

Purpose: Monitoring radiation dose and time parameters during radiological interventions is crucial, especially in neurointerventional procedures, such as aneurysm treatment with embolization coils. The algorithm presented detects the presence of these embolization coils in medical images. It establishes a bounding box as a reference for automated collimation, with the primary objective being to enhance the efficiency and safety of neurointerventional procedures by actively optimizing image quality while minimizing patient dose.

Methods: Two distinct methodologies are evaluated in our study. The first involves deep learning, employing the Faster R-CNN model with a ResNet-50 FPN as a backbone and a RetinaNet model. The second method utilizes a classical blob detection approach, serving as a benchmark for comparison.

Results: We performed a fivefold cross-validation, and our top-performing model achieved mean mAP@75 of 0.84 across all folds on validation data and mean mAP@75 of 0.94 on independent test data. Since we use an upscaled bounding box, achieving 100% overlap between ground truth and prediction is not necessary. To highlight the real-world applications of our algorithm, we conducted a simulation featuring a coil constructed from an alloy wire, effectively showcasing the implementation of automatic collimation. This resulted in a notable reduction in the dose area product, signifying the reduction of stochastic risks for both patients and medical staff by minimizing scatter radiation. Additionally, our algorithm assists in avoiding extreme brightness or darkness in X-ray angiography images during narrow collimation, ultimately streamlining the collimation process for physicians.

Conclusion: To our knowledge, this marks the initial attempt at an approach successfully detecting embolization coils, showcasing the extended applications of integrating detection results into the X-ray angiography system. The method we present has the potential for broader application, allowing its extension to detect other medical objects utilized in interventional procedures.

优化神经介入手术:栓塞线圈检测和自动准直以减少剂量的算法。
目的:监测放射介入过程中的辐射剂量和时间参数至关重要,尤其是在神经介入手术中,如使用栓塞线圈治疗动脉瘤。本文介绍的算法可检测医学图像中是否存在这些栓塞线圈。它建立了一个边界框,作为自动准直的参考,主要目的是通过积极优化图像质量,同时最大限度地减少患者剂量,提高神经介入手术的效率和安全性:我们的研究评估了两种不同的方法。第一种方法涉及深度学习,采用以 ResNet-50 FPN 为骨干的 Faster R-CNN 模型和 RetinaNet 模型。第二种方法采用经典的 Blob 检测方法,作为比较基准:我们进行了五倍交叉验证,在验证数据上,我们的最高性能模型在所有褶皱中的平均 mAP@75 为 0.84,在独立测试数据上的平均 mAP@75 为 0.94。由于我们使用的是放大的边界框,因此不需要在地面实况和预测之间实现 100% 的重叠。为了突出我们算法在现实世界中的应用,我们进行了一次模拟,模拟的线圈是由合金丝构成的,有效地展示了自动准直的实现。这显著降低了剂量面积乘积,通过最大限度地减少散射辐射,降低了患者和医务人员的随机风险。此外,我们的算法还有助于避免 X 射线血管造影图像在窄准直过程中出现极亮或极暗的情况,最终简化了医生的准直过程:据我们所知,这是成功检测栓塞线圈方法的首次尝试,展示了将检测结果集成到 X 射线血管造影系统中的扩展应用。我们提出的方法具有更广泛的应用潜力,可扩展到检测介入手术中使用的其他医疗物体。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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